Evidence map›Paper›PMID 40672394›Full record

ReviewFrontiers in genetics2025

Conceptualizing the public good for genomics in the global South: a cross-disciplinary roundtable dialogue.

Tayyaba Jiwani, Adjua Akinwumi, Jocelyn Cheé-Santiago, Yulia Egorova, Gabriel Frassetto, Ricardo di Lazzaro Filho, Iscia Lopes-Cendes, Mercedes Okumura, José Antonio Alonso Pavón, Alice B Popejoy and 5 more

Abstract readReview
In one paragraph

Review in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tayyaba JiwaniDepartment of Sociology, Philosophy, and Anthropology, University of Exeter, Exeter, United Kingdom.
Adjua AkinwumiSchool of Communication, Simon Fraser University, Burnaby, BC, Canada.
Jocelyn Cheé-SantiagoSchool of Life Sciences, Arizona State University, Tempe, AZ, United States.
Yulia EgorovaDepartment of Anthropology, University of Durham, Durham, United Kingdom.
Gabriel FrassettoDepartment of Genetics and Evolutionary Biology, Biosciences Institute, University of São Paulo, SãoPaulo, Brazil.
Ricardo di Lazzaro FilhoDasa Genômica/Genera, Genômica, SãoPaulo, Brazil.
Iscia Lopes-CendesDepartment of Medical Genetics and Genomic Medicine, School of Medical Sciences; and Brazilian Institute of Neuroscience and Neurotechnology (BRAINN), University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
Mercedes OkumuraDepartment of Genetics and Evolutionary Biology, Biosciences Institute, University of São Paulo, SãoPaulo, Brazil.
José Antonio Alonso PavónFaculty of Sciences, National Autonomous University of Mexico (UNAM), México City, Mexico.
Alice B PopejoyDepartment of Public Health Sciences, University of California, Davis, United States.
David SkinnerSchool of Humanities and Social Sciences, Anglia Ruskin University, Cambridge, United Kingdom.
Peter WadeDepartment of Social Anthropology, University of Manchester, Manchester, United Kingdom.
Matthias WienrothSchool of Humanities and Social Sciences, Northumbria University, Newcastle-upon-Tyne, United Kingdom.
Ernesto Schwartz-MarinDepartment of Sociology, Philosophy, and Anthropology, University of Exeter, Exeter, United Kingdom.
Michel Satya NaslavskyDepartment of Genetics and Evolutionary Biology, Biosciences Institute, University of São Paulo, SãoPaulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the Human Genome Project, initiatives to genetically sequence and profile populations around the world have expanded rapidly. The rationales guiding this expansion are diverse: on the one hand, the concentration of genetic technologies in the global North threatens to widen the yawning gaps in healthcare available in advanced versus developing nations. On the other, more 'genetic diversity' in global databases can reveal new points of genetic variation associated with health or disease. This promises to pave the way to a more personalized medicine of the future-more powerful and prosperous, with tailored prevention regimens and genetic treatments targeted to every individual's specific genetic vulnerabilities. These rationales are advanced to claim a public good case for genomics. However, the expansion of genomics to underserved populations in the global South has provoked many sociopolitical and ethical challenges. Critics have pointed to the inevitable entanglement of genomics with private commercial interests. These concerns are overlaid on deeper anxieties stemming from global asymmetries in scientific and technological power, and historical patterns of value extraction from colonized and marginalized populations. How then do we disentangle the public good? How do we build a genomics science that is just and equitable for the vast majority of the world? This conversation convenes leading genomics practitioners and critical science studies scholars to address these questions. We draw on an ongoing transdisciplinary dialogue, integrating the natural and social sciences, and bring together perspectives and scholars from the global North and South. Our aim is to cultivate a more holistic and grounded engagement with the scientific and political challenges we face, to truly understand the requirements of a genomics that centers the question of justice.

Indexed as

capitalismgenetic diversitygenomicsgovernanceinequalityjusticepublic-privatesovereignty

Identifiers

PMID40672394
PMCPMC12264638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.