Evidence map›Paper›PMID 40672328›Full record

ArticlebioRxiv : the preprint server for biology2026

Trimester-Dependent Vertical Transmission of H5N1 Influenza Virus Through Placental and Mammary Routes Impairs Offspring Development.

Brittany A Seibert, Maclaine A Parish, Sattya N Talukdar, Tianle Zhang, Jennifer A Liu, Sabal Chaulagain, Jaiprasath Sachithanandham, Oscar Hernandez, Cosette Schneider, Lynda Coughlan and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Brittany A SeibertORCID 0000-0002-5721-5382
Maclaine A ParishORCID 0000-0002-1442-7633
Sattya N Talukdar
Tianle Zhang
Jennifer A Liu
Sabal Chaulagain
Jaiprasath Sachithanandham
Oscar Hernandez
Cosette Schneider
Lynda Coughlan
Andrew S BowmanORCID 0000-0002-0738-8453
Richard J Webby
Jack R Harkema
Andrew PekoszORCID 0000-0003-3248-1761
Sabra L KleinORCID 0000-0002-0730-5224

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00045 · NIAID · JOHNS HOPKINS UNIVERSITY · PI PEKOSZ, ANDREW · 2021 to 2025
$23.3M
Training: Molecular & Cellular Bases of Infectious DiseasesT32AI007417 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Arturo Casadevall · 1994 to 2026
$11.9M
Microbiome-induced changes following influenza infection during pregnancyF32HD117584 · NICHD · JOHNS HOPKINS UNIVERSITY · PI Brittany Anne Seibert · 2025 to 2026
$156k
Investigation of neuraminidase as a target antigen for a universal influenza virus vaccineF31AI183628 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Cosette Schneider · 2025 to 2026
$85k
NIAID NIH HHS 75N93021C00045NIAID NIH HHS F31 AI183628NIAID NIH HHS T32 AI007417NICHD NIH HHS F32 HD117584
6 · The paper itself

Abstract

Avian influenza H5N1 has pandemic potential and historically has caused more severe disease in pregnant women than the general population. With increasing transmission of H5N1 detected among placental mammals, animal models are necessary for testing countermeasures, including during pregnancy. Pregnant outbred mice were infected with a contemporary strain of bovine H5N1 during the second or third trimester equivalent. Second trimester infection caused

Identifiers

PMID40672328
PMCPMC12265628

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.