Evidence map›Paper›PMID 40672326›Full record

ArticlebioRxiv : the preprint server for biology2025

Dichotomous transcriptome divergence at the cell-type level between the

Imtiyaz E Hariyani, Sudeshna Das, Emma M Le, Carmen Gamero-Castano, Tina Soroudi, Joshua Choi, Vivek Swarup, Jose M Ranz

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Imtiyaz E HariyaniDepartment of Ecology and Evolutionary Biology, University of California Irvine, CA 92697, USA.ORCID 0000-0003-2657-9842
Sudeshna DasDepartment of Neurobiology and Behavior, University of California Irvine, CA 92697, USA.
Emma M LeDepartment of Ecology and Evolutionary Biology, University of California Irvine, CA 92697, USA.
Carmen Gamero-CastanoDepartment of Ecology and Evolutionary Biology, University of California Irvine, CA 92697, USA.
Tina SoroudiDepartment of Ecology and Evolutionary Biology, University of California Irvine, CA 92697, USA.
Joshua ChoiDepartment of Ecology and Evolutionary Biology, University of California Irvine, CA 92697, USA.
Vivek SwarupDepartment of Neurobiology and Behavior, University of California Irvine, CA 92697, USA.ORCID 0000-0003-3762-2746
Jose M RanzDepartment of Ecology and Evolutionary Biology, University of California Irvine, CA 92697, USA.ORCID 0000-0003-3585-3129

Funding

Oligodendrocyte heterogeneity in Alzheimer' s diseaseR01AG071683 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI SWARUP, VIVEK · 2024 to 2025
$1.2M
NIA NIH HHS R01 AG071683
6 · The paper itself

Abstract

Gene expression evolution in reproductive organs plays a central role in species divergence, yet cell-type-resolved patterns in invertebrates remain poorly understood. We used single-nucleus RNA-sequencing to profile testis and ovary transcriptomes from the sibling species

Indexed as

D. melanogaster species subgroupgene expressiongermline evolutionsnRNA-seqtranscriptome evolution

Identifiers

PMID40672326
PMCPMC12265674

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.