Evidence map›Paper›PMID 40672313›Full record

ArticlebioRxiv : the preprint server for biology2025

Robust regulatory interplay of enhancers, facilitators, and promoters in a native chromatin context.

Zhou Zhou, Albert Li, Junke Zhang, Haiyuan Yu, Abdullah Ozer, John T Lis

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Zhou ZhouDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-2856-7116
Albert LiCollege of Agriculture and Life Sciences, Cornell University, Ithaca, NY 14853, USA.
Junke ZhangDepartment of Computational Biology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-2178-1307
Haiyuan YuDepartment of Computational Biology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-7597-6049
Abdullah OzerDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-6861-2853
John T LisDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-1201-9406

Funding

Functional Architecture and Interplay of Transcription Regulatory Elements of the Human GenomeR01HG012970 · NHGRI · CORNELL UNIVERSITY · PI JOHN T LIS, Haiyuan Yu · 2023 to 2026
$2.7M
NHGRI NIH HHS R01 HG012970
6 · The paper itself

Abstract

Enhancers are gene-distal

Identifiers

PMID40672313
PMCPMC12265581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.