Evidence map›Paper›PMID 40672258›Full record

ArticlebioRxiv : the preprint server for biology2025

A Bioelectrochemical Crossbar Architecture Screening Platform (BiCASP) for Extracellular Electron Transfer.

Hasika Suresh, Presley Bird, Kundan Saha, Surya Varchasvi Devaraj, Cihan Asci, Albert Truong, Cooper Wallman, Rhea Patel, Atul Sharma, Matthew D Carpenter and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hasika SureshSonkusale Research Labs, Tufts University, 171 College Avenue, Medford, MA 02155, USA.ORCID 0000-0002-1108-4858
Presley BirdDepartment of BioSciences, Rice University, 6100 Main Street, MS-140, Houston, TX, 77005, USA.
Kundan SahaSonkusale Research Labs, Tufts University, 171 College Avenue, Medford, MA 02155, USA.ORCID 0000-0001-7401-5676
Surya Varchasvi DevarajSonkusale Research Labs, Tufts University, 171 College Avenue, Medford, MA 02155, USA.ORCID 0000-0002-9168-406X
Cihan AsciSonkusale Research Labs, Tufts University, 171 College Avenue, Medford, MA 02155, USA.ORCID 0009-0009-3972-6099
Albert TruongDepartment of BioSciences, Rice University, 6100 Main Street, MS-140, Houston, TX, 77005, USA.ORCID 0009-0001-3235-1708
Cooper WallmanSonkusale Research Labs, Tufts University, 171 College Avenue, Medford, MA 02155, USA.
Rhea PatelSchool of Chemical Science, Goa University, Taleigao Plateau, Goa, 403206, India.ORCID 0000-0001-6819-8015
Atul SharmaSonkusale Research Labs, Tufts University, 171 College Avenue, Medford, MA 02155, USA.ORCID 0000-0003-0877-1275
Matthew D CarpenterDepartment of BioSciences, Rice University, 6100 Main Street, MS-140, Houston, TX, 77005, USA.ORCID 0000-0003-0310-2881
Sujitkumar BontapalleDepartment of Chemical and Biomolecular Engineering, Rice University, 6100 Main Street, MS-362, Houston, TX, 77005, USA.ORCID 0000-0001-9541-5898
Rafael VerduzcoDepartment of Chemical and Biomolecular Engineering, Rice University, 6100 Main Street, MS-362, Houston, TX, 77005, USA.ORCID 0000-0002-3649-3455
Jonathan J SilbergDepartment of BioSciences, Rice University, 6100 Main Street, MS-140, Houston, TX, 77005, USA.ORCID 0000-0001-5612-0667
Sameer SonkusaleSonkusale Research Labs, Tufts University, 171 College Avenue, Medford, MA 02155, USA.ORCID 0000-0003-3579-910X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electroactive microbes can be used as components in electrical devices to leverage their unique behavior for biotechnology, but they remain challenging to engineer because the bioelectrochemical systems (BES) used for characterization are low-throughput. To overcome this challenge, we describe the development of the Bioelectrochemical Crossbar Architecture Screening Platform (BiCASP), which allows for samples to be arrayed and characterized in individually addressable microwells. This device reliably reports on the current generated by electroactive bacteria on the minute time scale, decreasing the time for data acquisition by several orders of magnitude compared to conventional BES. Also, this device increased the throughput of screening engineered biological components in cells, quickly identifying mutants of the membrane protein wire MtrA in

Indexed as

Arrayed microwellsbioelectrochemical systemsbioelectronicscrossbar architecturedecaheme proteinelectrical multiplexelectroactive microbeextracellular electron transferhigh-throughput screeningShewanella

Identifiers

PMID40672258
PMCPMC12265703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.