Evidence map›Paper›PMID 40672157›Full record

ArticlebioRxiv : the preprint server for biology2025

Modeling Laryngeal Dystonia through Spectral Analyses of Vocalizations in a Dystonia Mouse Model.

Austin L Fitzgerald, Jonathan A Coello, Alyssa M Lyon, Breanne L Dao, Meike E van der Heijden

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Austin L FitzgeraldFralin Biomedical Research Institute at Virginia Tech Carilion School of Medicine.ORCID 0009-0000-9688-1612
Jonathan A CoelloFralin Biomedical Research Institute at Virginia Tech Carilion School of Medicine.ORCID 0009-0008-8947-5665
Alyssa M LyonFralin Biomedical Research Institute at Virginia Tech Carilion School of Medicine.ORCID 0009-0009-8781-558X
Breanne L DaoFralin Biomedical Research Institute at Virginia Tech Carilion School of Medicine.ORCID 0009-0009-8135-4428
Meike E van der HeijdenFralin Biomedical Research Institute at Virginia Tech Carilion School of Medicine.ORCID 0000-0003-0801-8806

Funding

Defining a Dystonia Specific Spiking Signature in Cerebellar Nuclei CellsR00NS130463 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Meike Esther Van Der Heijden · 2024 to 2026
$740k
NINDS NIH HHS R00 NS130463
6 · The paper itself

Abstract

Laryngeal dystonia is a task-specific, focal dystonia that disrupts vocal-motor control and significantly alters quality of life through impaired communication. Despite its early onset in many hereditary dystonias, effective treatments remain limited, in part due to the lack of a preclinical model that captures its circuit-level pathophysiology. Our experiment evaluates ultrasonic vocalizations (USVs) in

Indexed as

cerebellar dysfunctionlaryngeal dystoniamouse modelspasmodic dysphoniatranslational neuroscienceultrasonic vocalizations

Identifiers

PMID40672157
PMCPMC12265613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.