ArticleJournal of gastrointestinal oncology2025
Lower diffusion-derived vessel density (DDVD) measure of liver focal nodular hyperplasia than those of hepatocellular carcinoma and liver metastasis allows potential differential diagnosis: quantitative and semi-quantitative analyses of two-center data.
Article in Journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed.
- The role of number-of-excitations (NEX) for the usability of free-breathing acquired diffusion-derived 'vessel density' (DDVD) and slow diffusion coefficient (SDC) maps in separating liver cysts, hemangiomas, and solid masses with a focus on small lesions.Journal of gastrointestinal oncology · 2026Article
- The impacts of time of echo and time of repetition on slow diffusion coefficient (SDC) measure and the potential age- and gender-related variations in liver and spleen SDC values: studies of healthy volunteers.Quantitative imaging in medicine and surgery · 2026Article
- Separation of liver focal nodular hyperplasia (FNH) and liver malignant tumors by a combination of T2-weighted imaging signal and three diffusion magnetic resonance metrics of diffusion-derived vessel density, slow diffusion coefficient, and apparent diffusion coefficient.Journal of gastrointestinal oncology · 2026Article
- Reliable diagnosis of liver focal nodular hyperplasia by a combination of T2 weighted signal and three diffusion magnetic resonance metrics of diffusion-derived 'vessel density', slow diffusion coefficient, and apparent diffusion coefficient: a validation study of two centers' data.Quantitative imaging in medicine and surgery · 2026Article
- An explanation for why tissues with T2 of around 70 milliseconds always measure low MRI apparent diffusion coefficient (ADC).Quantitative imaging in medicine and surgery · 2025Article
- A combination of MRI diffusion-derived vessel density (DDVD) and slow diffusion coefficient (SDC) can reliably diagnose liver hemangioma: a testing of three centers' data.Journal of gastrointestinal oncology · 2025Article
- Dual-energy computed tomography-derived electron density in the differential diagnosis of focal hepatic lesions: initial experience.Quantitative imaging in medicine and surgery · 2025Article
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10 authors.
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Abstract
Background: Focal nodular hyperplasia (FNH) and liver cancers are commonly differentiated by contrast enhanced scan, particularly with the application of hepatobiliary-specific contrast agents. This study aims to investigate the diffusion-derived vessel density (DDVD) difference between liver FNH and liver malignant lesions [hepatocellular carcinoma (HCC) and metastasis]. Methods: The liver diffusion-weighted magnetic resonance imaging (MRI) dataset-1 had 8 cases of FNH, 56 cases of HCC, and 14 cases of liver metastases. Liver diffusion MRI dataset-2 had 10 cases of FNH, 78 cases of HCC. For dataset-1, DDVD Results: FNH tended to have a lower DDVDr value than malignant lesions, both for dataset-1 (mean DDVDr Conclusions: FNH has a lower DDVD measure compared to HCC and Mets. A drop from DWI high signal or slightly high signal to DDVD iso-signal suggests the diagnosis of FNH.
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