ArticleJournal of gastrointestinal oncology2025
Clinical and endoscopic characteristics of colorectal sessile serrated lesion with dysplasia: a single-center cross-sectional comparative study.
Article in Journal of gastrointestinal oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The precancerous lesion of colorectal cancer (CRC), colorectal sessile serrated lesion (SSL), takes an average of 15 years to germinate from no cell dysplasia to CRC, and 2 years for SSL with dysplasia (SSL-D). To date, the impacts of endoscopic and pathological features of SSL and SSL-D on the development of dysplasia remain unclear. In this study, we explored these impacts, striving to provide reference for its classification, detection, and diagnosis. Methods: Retrospectively, a cross-sectional analysis was conducted to compare 414 SSL and 59 SSL-D, which had been diagnosed under colonoscopy in the Affiliated Drum Tower Hospital of Nanjing University. Results: A total of 454 participants were enrolled with a mean age of 58.43±13.94 years and a male-to-female ratio of 0.91:1. There were significant differences between the SSL and SSL-D groups in the gender distribution (P=0.044). The proportion of patients with hypertension (33.33% Conclusions: Female SSL patients with a history of hypertension are more prone to developing into dysplasia, whereas morphological discriminations between SSL and SSL-D are vague. Lipid metabolism might have certain impact on the germination of SSL to SSL-D. Studies with larger sample sizes are warranted.
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