Evidence map›Paper›PMID 40671912›Full record

ArticleFrontiers in endocrinology2025

A study on the diagnostic value of artificial intelligence combined with a contrast-enhanced ultrasound scoring system in partially cystic thyroid carcinoma.

Xiao-Hui Yan, Qian Chen, Yu-Wei Xin, Si-Jie Yuan, Jing-Jing Liu, Hai-Yan Jia, Wen-Ya, Yan-Jing Zhang, Wen-Wen Fan, Yu-Fang Zhao and 2 more

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiao-Hui Yan *Department of Interventional Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Qian Chen *Department of Urology Surgery, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.
Yu-Wei XinDepartment of Ultrasound, Peking University People's Hospital, Beijing, China.
Si-Jie YuanDepartment of Ultrasound, Shanxi Bethune Hospital, Taiyuan, Shanxi, China.
Jing-Jing LiuDepartment of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Hai-Yan JiaDepartment of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Wen-YaDepartment of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Yan-Jing ZhangDepartment of Interventional Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Wen-Wen FanDepartment of Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Yu-Fang ZhaoDepartment of Interventional Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Liang-PingDepartment of Interventional Ultrasound, Fifth Medical Center of Chinese People's Liberation Army (PLA) General Hospital, Beijing, China.
Li-Ping LiuDepartment of Interventional Ultrasound, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The aim of this study was to investigate the diagnostic value of the contrast-enhanced ultrasound (CEUS) scoring system, artificial intelligence (AI) and the American College of Radiology Thyroid Imaging and Reporting Data System when used by sonographers of different seniority levels individually and in combination for the diagnosis of partial cystic thyroid nodules (PCTNs). Materials and methods: A retrospective analysis of conventional ultrasound and CEUS images of enrolled patients was performed, and a CEUS scoring system was established. The sensitivity, specificity, and area under the curve (AUC) of CEUS and AI individually and in combination for diagnosis were compared among sonographers with different seniority levels. Results: A total of 166 nodules (83 benign and 83 malignant) from 152 patients with PCTNs were analyzed in this study. Nine CEUS features of PCTNs were observed and summarized; eight of these features differed between the two groups (all Conclusions: The CEUS scoring system established in this study has high diagnostic value for PCTNs. The use of CEUS and AI can improve the diagnostic accuracy of sonographers and improve the prognosis of PCTN patients.

Indexed as

Artificial IntelligenceContrast MediaCystsThyroid NeoplasmsThyroid NoduleAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesUltrasonographyYoung AdultContrast MediaACR TI-RADSartificial intelligence (AI)contrast-enhanced ultrasound (CEUS)partial cystic thyroid nodulesscoring system

Identifiers

PMID40671912
PMCPMC12263380

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.