Evidence map›Paper›PMID 40671880›Full record

ArticleGenetics in medicine open2025

Genomic insights into Rett syndrome-like features in Bangladeshi participants.

Hosneara Akter, Muhammad Mizanur Rahman, Rabeya Akter Mim, Atikur Rahaman, Tamannyat Binte Eshaque, Syed Akib Hossain, Athoi Ganguly, Farjana Binta Omar, Masuma Afrin Taniya, Nahid Hasan and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics in medicine open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Hosneara AkterGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
Muhammad Mizanur RahmanDepartment of Paediatric Neurology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
Rabeya Akter MimGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
Atikur RahamanGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
Tamannyat Binte EshaqueGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
Syed Akib HossainLaboratory of Gut-Brain Axis, Infection Diseases Division, International Center for Diarrheal Disease Research Bangladesh (icddr,b), Dhaka, Bangladesh.
Athoi GangulyGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
Farjana Binta OmarGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
Masuma Afrin TaniyaGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
Nahid HasanGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
Amirul IslamGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
Bassam JamalalailCenter for Applied and Translational Genomics (CATG), Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Nasna NassirCenter for Applied and Translational Genomics (CATG), Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Binte ZehraCenter for Applied and Translational Genomics (CATG), Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Shaoli SarkerDepartment of Child Neurology, NeuroGen Healthcare, Dhaka, Bangladesh.
K M Furkan UddinGenetics and Genomic Medicine Centre, NeuroGen Healthcare, Dhaka, Bangladesh.
A H M Nurun NabiDepartment of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh.
Marc Woodbury-SmithBiosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
Mohammed UddinGenomeArc Inc., Mississauga, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Rett syndrome (RTT) is a neurological disorder marked by the loss of developmental milestones. Classic RTT involves variants in the methyl-CpG-binding protein 2 ( Methods: Results: Of the 27 participants, 51.9% (14/27) had pathogenic Conclusion: This genetic study of clinically diagnosed Bangladeshi RTT participants identifies new genes involved in the etiology of RTT-like phenotypes and expands the phenotypic spectrum of known genes linked to neurodevelopmental disorders.

Indexed as

Exome sequencingGenomeArc HorizonNeurodevelopmental disordersRett syndromeTargeted sequencing

Identifiers

PMID40671880
PMCPMC12266481

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.