Evidence map›Paper›PMID 40671877›Full record

ArticleMitochondrial communications2025

Exploring the oncogenic impact of heteroplasmic

Yuanyuan Wu, Jiangbin Ye, Zhenglong Gu

Abstract read
In one paragraph

Article in Mitochondrial communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuanyuan WuDivision of Nutritional Sciences, Cornell University, Savage Hall, Ithaca, 14850, NY, USA.ORCID 0000-0002-4599-0162
Jiangbin YeDepartment of Radiation Oncology, Stanford University School of Medicine, 94305, CA, USA.ORCID 0000-0003-1117-4869
Zhenglong GuDivision of Nutritional Sciences, Cornell University, Savage Hall, Ithaca, 14850, NY, USA.

Funding

Ethnic Differences in Iron AbsorptionR01DK122216 · NIDDK · CORNELL UNIVERSITY · PI O'BRIEN, KIMBERLY O · 2019 to 2022
$2.2M
NIDDK NIH HHS R01 DK122216
6 · The paper itself

Abstract

Numerous mitochondrial DNA (mtDNA) variants are associated with cancers, yet the causal link remains inconclusive. Using DddA-derived cytosine base editors, we induced

Indexed as

Mitochondrial dysfunctionmtDNA heteroplasmyMT-ND5 variantsOncogenesis

Identifiers

PMID40671877
PMCPMC12266708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.