Evidence map›Paper›PMID 40671854›Full record

ArticleJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada2025

Evolution and Possible Explanations for the Trends in New HIV Diagnoses in Alberta, Saskatchewan, and Manitoba, Compared to the Rest of Canada, 1985-2022.

Zulma Vanessa Rueda, Luisa Arroyave, Mariana Herrera, Ameeta E Singh, Stuart Skinner, Cara Spence, Lauren J MacKenzie, Ken Kasper, Laurie Ireland, Julianne Sanguins and 3 more

Abstract read
In one paragraph

Article in Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Epidemiology and infection · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zulma Vanessa RuedaDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg Manitoba, Canada.
Luisa ArroyaveNational Collaborating Centre for Infectious Diseases (NCCID), University of Manitoba, Winnipeg, Manitoba, Canada.
Mariana HerreraDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg Manitoba, Canada.
Ameeta E SinghDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Stuart SkinnerDepartment of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Cara SpenceDepartment of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Lauren J MacKenzieDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Ken KasperDepartment of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Laurie IrelandManitoba HIV Program, Winnipeg, Manitoba, Canada.
Julianne SanguinsDepartment of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Katharina MaierDepartment of Criminal Justice, University of Winnipeg, Winnipeg, Manitoba, Canada.
Margaret Haworth-BrockmanNational Collaborating Centre for Infectious Diseases (NCCID), University of Manitoba, Winnipeg, Manitoba, Canada.
Yoav KeynanDepartment of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg Manitoba, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Canada aims to end the HIV epidemic as a public health threat by 2030. However, the provinces Alberta, Saskatchewan, and Manitoba reported 564 new HIV diagnoses in 2021 and over 600 in 2022. This study describes changes in HIV epidemiology in these three provinces compared to the rest of Canada between 1985 and 2022. Methods: This was an ecological study that used data from publicly available HIV reports published by the Governments of Manitoba, Saskatchewan, Alberta, and Canada from the first reported HIV diagnoses to the latest available information. Variables of interest included number of HIV diagnoses per year (new, introduced), advanced HIV disease, proportion of diagnoses by sex (female/male), ethnicity, age, self-reported HIV mode of transmission, and mortality. We report the HIV incidence, advanced HIV disease, and mortality over time by province, and by sex, ethnicity, age, and mode of HIV transmission when data are available. Results: Canadian HIV incidence decreased over time, while new HIV diagnoses in Manitoba and Saskatchewan increased to the highest ever recorded. In Saskatchewan and Manitoba, the male-to-female ratio is 1:1, while in Alberta and Canada, it is 2:1. Indigenous people have been overrepresented in Saskatchewan and Manitoba diagnoses since 2006 and 2016, respectively. The most common modes of HIV transmission are injection drug use and heterosexual sex in Saskatchewan and Manitoba for several years, while "out-of-country" is the most common category in Alberta. The advanced HIV disease and mortality statistics have decreased over time in Canada and the three provinces. Conclusion: HIV incidence in Canada has slowly decreased; however, Manitoba and Saskatchewan have shown unprecedented increases in HIV incidence. The current epidemiology requires immediate public health action from local, provincial, and federal governments, considering that Alberta, Saskatchewan, and Manitoba contribute to about 40% of all new HIV diagnoses in Canada.

Indexed as

AlbertaCanadaecological studyethnicityHIVManitobaSaskatchewansex

Identifiers

PMID40671854
PMCPMC12258641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.