ArticleEFSA journal. European Food Safety Authority2025
Safety of a feed additive consisting of folic acid for aquatic species (Chr. Olesen A/S and DSM Nutritional Products Ltd).
Article in EFSA journal. European Food Safety Authority, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Safety of a feed additive consisting of folic acid for aquatic species (Chr. Olesen A/S and DSM Nutritional Products Ltd).EFSA journal. European Food Safety Authority · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety of a feed additive consisting of folic acid intended for use as a nutritional additive (functional group: vitamins, pro-vitamins and chemically well-defined substances having similar effects) for aquatic species. The characterisation, safety and efficacy of the additive have been assessed previously, however the FEEDAP Panel, considering the narrow margin between the requirement and the tolerated levels seen in some aquatic animal species, could not set a maximum safe level for all fish and crustacean species and considered that supplementation should not exceed the requirements of the different aquatic animal species. In addition, the FEEDAP Panel recommended that further research is conducted to allow setting a maximum safe level of folic acid in aquatic animal species. In the present assessment, the applicant submitted new information retrieved with an extensive literature search. After the assessment of the data newly submitted, the FEEDAP Panel reiterates its previous conclusions that the use of folic acid in aquatic animal species to cover their nutritional needs is considered safe. However, the Panel is not in a position to set maximum safe levels for all fish, crustacean and molluscs species. Considering the narrow margin between the requirement and the tolerated levels seen in some aquatic animal species, the FEEDAP Panel considers that supplementation should not exceed the requirements of the different aquatic animal species recognised by International scientific organisations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.