Evidence map›Paper›PMID 40671802›Full record

ArticleResearch square2025

CHLOK: a chemigenetic multicolor labeling system to visualize neuronal birthdate and circuit integration.

Giulia Faini, Matthieu Tuffery, Amna Saleem, Lixia Zhang, Felix Du, Guillaume Le Bourdelles, Karine Duroure, Eric Schreiter, Dimitrii Tanese, Valentina Emiliani and 2 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Giulia FainiInstitut de la Vision, Sorbonne Univ., Inserm S968, CNRS UMR7210, Paris, France.ORCID 0000-0002-8029-6205
Matthieu TufferyInstitut de la Vision, Sorbonne Univ., Inserm S968, CNRS UMR7210, Paris, France.
Amna SaleemDepartment of Biological Sciences, University of Toronto Scarborough, Toronto, Canada.
Lixia ZhangJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
Felix DuDepartment of Biological Sciences, University of Toronto Scarborough, Toronto, Canada.ORCID 0009-0009-1043-6055
Guillaume Le BourdellesInstitut de la Vision, Sorbonne Univ., Inserm S968, CNRS UMR7210, Paris, France.ORCID 0009-0009-6086-607X
Karine DuroureInstitut de la Vision, Sorbonne Univ., Inserm S968, CNRS UMR7210, Paris, France.ORCID 0000-0002-5959-569X
Eric SchreiterJanelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.ORCID 0000-0002-2864-7469
Dimitrii TaneseInstitut de la Vision, Sorbonne Univ., Inserm S968, CNRS UMR7210, Paris, France.ORCID 0000-0002-9696-962X
Valentina EmilianiInstitut de la Vision, Sorbonne Univ., Inserm S968, CNRS UMR7210, Paris, France.ORCID 0000-0003-2992-9510
Filippo Del BeneInstitut de la Vision, Sorbonne Univ., Inserm S968, CNRS UMR7210, Paris, France.ORCID 0000-0001-8551-2846
Minoru KoyamaDepartment of Biological Sciences, University of Toronto Scarborough, Toronto, Canada.

Funding

Zooming into the fish's brain-What is really going on! Connectomics analysis of larval zebrafish.U19NS104653 · NINDS · HARVARD UNIVERSITY · PI MARK C FISHMAN · 2017 to 2026
$39.4M
NINDS NIH HHS U19 NS104653
6 · The paper itself

Abstract

Understanding how neurons integrate into developing circuits and contribute to functional activity is essential for decoding brain development and plasticity. However, current methods to study neuronal integration often suffer from low throughput, limited spatiotemporal resolution, or invasive procedures that hinder

Identifiers

PMID40671802
PMCPMC12265168

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.