ArticleWorld journal of clinical cases2025
Paravertebral soft tissue swelling on magnetic resonance images helps in differentiation between osteoporotic and malignant vertebral fractures.
Article in World journal of clinical cases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundOsteoporotic vertebral fracture (OVF) is one of the most common sequelae of osteoporosis. Differential diagnosis between OVF and malignant vertebral fracture (MVF) is a challenge in clinical practice. Findings on computed tomography and magnetic resonance images (MRI) may help to differentiate between these two types of fracture.
aimTo determine whether paravertebral soft tissue swelling is useful for differentiation between OVF and MVF.
methodsWe retrospectively reviewed the MRI for 165 patients diagnosed with a vertebral fracture between May 2021 and July 2022. Three radiologists evaluated the vertebral segments and thickness of soft tissue swelling on sagittal MRI by consensus. The morphology of the soft tissue swelling was also evaluated. The statistical analyses were performed using the
resultsThe study included 117 patients (153 vertebrae) with OVF and 48 patients (63 vertebrae) with MVF. Soft tissue swelling was observed beneath the anterior longitudinal ligament on sagittal MRI and rim-shaped in the paravertebral area on axial MRI in all 153 vertebrae with OVF (100%) and in 12 (19%) of the 63 vertebra with MVF; the difference was statistically significant (
conclusionParavertebral soft tissue swelling is helpful for differentiating between OVF and MVF.
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