Evidence map›Paper›PMID 40671733›Full record

ArticleJournal of diabetes and metabolic disorders2025

Proper diagnosis of latent autoimmune diabetes in adults prompts appropriate pharmacotherapy; C-peptide is just one component.

Jenna C Record, A Cole Eichelberger, Brianna L Johns, Gage T Bouziden, Jeremy L Johnson

Abstract readCase Reports
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jenna C RecordDepartment of Pharmacy, Oklahoma State University Medical Center, 744 W 9th St, Tulsa, OK USA.
A Cole EichelbergerDepartment of Pharmacy, Oklahoma State University Medical Center, 744 W 9th St, Tulsa, OK USA.
Brianna L JohnsDepartment of Pharmacy Practice, Southwestern Oklahoma State University College of Pharmacy, 100 Campus Dr, Weatherford, OK USA.
Gage T BouzidenDepartment of Pharmacy Practice, Southwestern Oklahoma State University College of Pharmacy, 100 Campus Dr, Weatherford, OK USA.
Jeremy L JohnsonDepartment of Pharmacy, Oklahoma State University Medical Center, 744 W 9th St, Tulsa, OK USA.ORCID 0000-0003-4001-5883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Latent Autoimmune Diabetes in Adults (LADA) is a type of diabetes that can phenotypically resemble type 2 diabetes upon initial presentation but expresses the autoimmune component of type 1 diabetes. While technically classed as type 1 diabetes, LADA is distinct from type 1 and 2 diabetes because of its intermediate progression that may or may not lead to complete insulin dependence. Differentiation is made with the presence or absence of autoantibodies and C-peptide. This is demonstrated in the following case. A 29-year-old Black female with a history of gestational diabetes and two-year history of prediabetes was ultimately diagnosed with type 2 diabetes with an A1c of 6.6% and was treated with metformin 500 mg twice daily. Her blood glucose suddenly rose to > 400 mg/dL and A1c to 8.6% after 8 months of therapy. Her BMI was 22.45 kg/m

Indexed as

Adult-onset diabetesDiabetesLADALADA misdiagnosisLatent autoimmune diabetes in adultsType 1.5 diabetes

Identifiers

PMID40671733
PMCPMC12259510

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.