Evidence map›Paper›PMID 40671691›Full record

ArticleRisk management and healthcare policy2025

Evaluating the Effectiveness of Spousal Testing Among Syphilis-Infected Pregnant Women in the Context of Mother-to-Child Transmission Elimination: A Multicenter Study in Southeastern China.

Xiaomeng Xue, Xinxin Huang, Guihua Liu, Xiumin Jiang, Wenzhao Lin, Yongfan Chen, Chengyu Huang

Abstract read
In one paragraph

Article in Risk management and healthcare policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaomeng Xue *School of Nursing, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
Xinxin Huang *The Ministry of Health, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
Guihua LiuNursing Department, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
Xiumin JiangNursing Department, Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
Wenzhao LinSchool of Nursing, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
Yongfan ChenSchool of Nursing, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.
Chengyu HuangSchool of Nursing, Fujian Medical University, Fuzhou, Fujian, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Syphilis during pregnancy poses significant risks to maternal and neonatal health. Spousal testing is crucial for preventing congenital syphilis transmission. This study assessed spousal testing rates among syphilis-positive pregnant women to guide public health interventions. Methods: This multicenter effectiveness study was conducted in Southeast China, utilizing data from the Chinese HIV/AIDS, Syphilis, and Hepatitis B Prevention Information System between 2018 to 2024. Proportions were used to describe the sociodemographic characteristics of pregnant women with syphilis. Univariate and multivariate unconditional logistic regression models were used to analyze the factors associated with the testing status of spouses of pregnant women with syphilis. Results: A total of 4,875 spouses were tested for syphilis. Older gestational age at the first prenatal visit (aOR = 1.014, 95% CI: 1.007-1.022) and at delivery (aOR = 1.273, 95% CI: 1.011-1.602) were associated with lower rates of spousal testing. Spouses of women reported in 2022-2023 (aOR = 1.840, 95% CI: 1.465-2.311) had a higher likelihood of being untested. Unmarried status (aOR = 1.181, 95% CI: 1.022-1.364), junior high school education and below (aOR = 1.244, 95% CI: 1.121-1.381), no history of infection (aOR = 2.281, 95% CI: 2.073-2.510), and prenatal care in Grade II hospitals (aOR = 0.1.292, 95% CI: 1.140-1.464) were risk factors for spousal testing. Conclusion: From 2018 to 2024, the spousal testing rate was 60%, with a syphilis positivity rate of 14.7%. Data revealed multiple risk factors, such as a late first pregnancy test, advanced age, unmarried status, lower education level, no history of syphilis infection, and selection of prenatal care in Grade II hospitals as delivery facilities. Recommendations include establishing specialized clinics, post-test spousal counseling, and routine spousal testing.

Indexed as

influencing factorsmulticenterpregnant womanspousal testingsyphilis

Identifiers

PMID40671691
PMCPMC12266062

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.