ArticleBiophysical journal2025
Viscosity and density measurements on the cytosol of human red blood cells.
Article in Biophysical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Impact of Red Blood Cell Deformability and Local Hematocrit on Microvascular Flow Resistance: Insights from In Vitro Microfluidic Measurements and Viscosity Modeling.Life (Basel, Switzerland) · 2026Article
- Band pattern formation of erythrocytes in density gradients is due to competing aggregation and net buoyancy.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
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Authors and funding
6 authors.
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Abstract
We introduce an approach for determining the viscosity of the intracellular liquid, called cytosol, of human red blood cells (RBCs). This methodology combines measurements of the mass density distribution of RBCs and the viscosity of the cytosol relative to its water content. The density distribution is obtained through buoyant density centrifugation paired with cell counting. By correlating the Gaussian distribution of cell population densities with the viscosity-density relationship of the cytosol, we derive a log-normal distribution of the cytosol viscosity in healthy RBCs. The viscosity contrast λ=η/η
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