Evidence map›Paper›PMID 40671557›Full record

Trial reportJournal of cosmetic dermatology2025

A Clinical Early Evaluation of the Combined Use of Low-Intensity Focused Ultrasound and Radiofrequency for Female Abdominal Contouring.

Zongzhou Wu, Yun Wang, Wei Li, Wei Zhang, Lian Zhu

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zongzhou WuDepartment of Cosmetology, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Yun WangDepartment of Hematology, Shanghai Putuo District Central Hospital, Shanghai, China.
Wei LiDepartment of Cosmetology, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Wei ZhangDepartment of Cosmetology, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Lian ZhuDepartment of Radiation Oncology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe growing incidence of adiposity has driven the innovation of potent non-invasive body contouring methodologies. Of these, low-intensity focused ultrasound (LIFU) therapy is recognized for its precision in targeting and destroying stubborn adipose tissue. This study aims to assess the treatment effectiveness and safety of utilizing LIFU in conjunction with radiofrequency for female abdominal contouring.

methodsA prospective clinical trial was performed with a cohort of 20 women, aged 28-42 years, who had a body mass index ranging from 20.40 to 26.82 kg/m

resultsThe treatment led to statistically significant reductions in supraumbilical, periumbilical, and subumbilical abdominal circumferences by 2.08 ± 3.29 cm (2.51%), 2.30 ± 3.23 cm (2.59%), and 3.03 ± 3.39 cm (3.29%), respectively. Similarly, significant decreases were observed in subcutaneous adipose tissue thickness at these sites by 6.46 ± 6.33 mm (27.37%), 6.03 ± 5.95 mm (23.28%), and 8.54 ± 6.94 mm (35.43%). On the other hand, dermal thickness demonstrated a mild increase of 9.17%, and none of the subjects experienced severe pain during the treatment sessions. Hematologic markers remained stable, and no adverse events were reported throughout the treatment period.

conclusionsThis investigation established that implementing low-intensity focused ultrasound alongside radiofrequency resulted in a secure and effective approach for abdominal contouring, contributing a novel strategy to medical practice.

Indexed as

Body ContouringRadiofrequency TherapyUltrasonic TherapyAbdomenAdultBody Mass IndexCombined Modality TherapyFemaleHumansProspective StudiesSubcutaneous Fat, AbdominalTreatment OutcomeUltrasonographyaesthetic medicinecosmetic dermatologycosmetic surgery

Identifiers

PMID40671557
PMCPMC12268313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.