Evidence map›Paper›PMID 40671549›Full record

ArticleJournal of the National Cancer Institute. Monographs2025

Mapping disparities: identifying cancer care gaps in sexual and gender minority patients.

Nicole L Simone, Sara Burke, Khaldoun Hamade, Amy Leader, Christopher McNair

Abstract read
In one paragraph

Article in Journal of the National Cancer Institute. Monographs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Comparative analysis of fatigue and mental health in sexual and gender minority cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicole L SimoneDepartment of Radiation Oncology, Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, Philadelphia, PA 19107, United States.ORCID 0000-0002-7662-7470
Sara BurkeDepartment of Radiation Oncology, Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, Philadelphia, PA 19107, United States.
Khaldoun HamadeDepartment of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, Philadelphia, PA 19107, United States.
Amy LeaderDepartment of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, Philadelphia, PA 19107, United States.
Christopher McNairDepartment of Medical Oncology, Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University, Philadelphia, PA 19107, United States.ORCID 0000-0003-3204-8482

Funding

X-Ray Crystallography and Macromolecular CharacterizationP30CA056036 · NCI · THOMAS JEFFERSON UNIVERSITY · PI Claudio Guillermo Giraudo · 1995 to 2026
$94.8M
NCI NIH HHS 5P30CA056036-17NCI NIH HHS P30 CA056036
6 · The paper itself

Abstract

backgroundSexual and gender minority (SGM) patients face disparities in cancer care, partly due to the lack of sexual orientation and gender identity (SOGI) data collection. We sought to use electronic health record-based metrics, integrated with SOGI data to characterize the SGM cancer population with the future goal of addressing disparities within this population.

methodsThe cancer population was identified using Epic's active cancer registry at Thomas Jefferson University Hospital. Additional data elements linked included SOGI information, general demographics, alcohol and drug use, molecular diagnostic information, and census-level SDOH data. Z-tests assessed differences in cancer risk factors, social vulnerability index factors, and genomic testing between the 2 populations.

resultsA total of 92 116 patients were identified from the active cancer registry with SOGI data available on 9544 patients (565 SGM and 8979 non-SGM patients). The SGM patients were younger, less likely to be married, and had higher rates of cancer associated risk factors. When comparing census-level social vulnerability data, SGM patients were overall more vulnerable. The groups had even representation of cancer types aside from higher anal cancer and Kaposi's sarcoma in the SGM population. No significant differences in cancer genomic testing were noted.

conclusionsThis study highlights the opportunities of integrating SOGI data with clinical and other data types, revealing disparities in cancer risk factors, social determinants of health, and specific cancer types. These findings emphasize the need for targeted interventions and personalized care to address the specific needs of SGM cancer patients and improve their health outcomes.

Indexed as

Healthcare DisparitiesNeoplasmsSexual and Gender MinoritiesAdultAgedFemaleHumansMaleMiddle AgedRegistriesRisk Factors

Identifiers

PMID40671549
PMCPMC12268168

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.