Evidence map›Paper›PMID 40671535›Full record

ArticleJournal of the National Cancer Institute. Monographs2025

Sexual orientation and gender identity data reveals real-world cancer disparities among sexual and gender minorities at an NCI-Designated Comprehensive Cancer Center.

Shahrzad A Zamani, Jaileene Pérez-Morales, Min-Jeong Yang, Gwendolyn P Quinn, Matthew B Schabath

Abstract read
In one paragraph

Article in Journal of the National Cancer Institute. Monographs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Identity among adolescent and young adult cancer survivors: an exploratory qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shahrzad A ZamaniDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States.ORCID 0000-0001-6730-2407
Jaileene Pérez-MoralesDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States.ORCID 0000-0003-3569-2396
Min-Jeong YangDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States.ORCID 0000-0002-0956-7041
Gwendolyn P QuinnPerlmutter Cancer Center, New York University Grossman School of Medicine, New York, NY, United States.ORCID 0000-0002-4208-9889
Matthew B SchabathDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States.ORCID 0000-0003-3241-3216

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Mindfulness-based ecological momentary intervention for smoking cessation among cancer survivorsR00CA271040 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Min-Jeong Yang · 2025 to 2026
$461k
Mindfulness-based ecological momentary intervention for smoking cessation among cancer survivorsK99CA271040 · NCI · H. LEE MOFFITT CANCER CTR & RES INST · PI YANG, MIN-JEONG · 2023 to 2024
$238k
Cancer CenterDesignated Comprehensive Cancer Center P30-CA076292Lee Moffitt Cancer Center & Research InstituteNCI NIH HHS K99 CA271040NCI NIH HHS K99/R00-CA271040NCI NIH HHS P30 CA076292NCI NIH HHS R00 CA271040
6 · The paper itself

Abstract

backgroundLack of sexual orientation and gender identity (SOGI) collection hinders the ability to identify cancer disparities, create opportunities for improvement, and reveal the burden of cancer among sexual and gender minority (SGM) populations. Our institution is one of the first NCI-Designated Comprehensive Cancer Centers to collect SOGI as standard-of-care demographics.

methodsThis analysis includes 118 320 patients who came to the H. Lee Moffitt Cancer Center & Research Institute ("Moffitt") between January 1, 2016 and December 31, 2023 and completed the institutional standard-of-care electronic patient questionnaire. Descriptive analyses were conducted to assessed overall and age-specific differences between SGM and non-SGM patients (ie, cisgender-heterosexual) for demographics, SOGI disclosure, clinical covariates, and psychosocial and quality-of-life needs.

resultsCompared with non-SGM patients, SGM patients were statistically significant younger, single, self-identified as racial and ethnic minorities, reported higher psychosocial and quality-of-life needs, and had higher-than-expected rates for several specific cancer sites.

conclusionsRevealing these real-world cancer disparities among SGM patients based on only 7 years of SOGI data collection highlights the fundamental importance of systematic collection of this demographic information for identifying and eventually mitigating health disparities.

Indexed as

Gender IdentityHealthcare DisparitiesHealth Status DisparitiesNeoplasmsSexual and Gender MinoritiesSexual BehaviorAdultAgedCancer Care FacilitiesFemaleHumansMaleMiddle AgedNational Cancer Institute (U.S.)Quality of LifeSurveys and Questionnaires

Identifiers

PMID40671535
PMCPMC12268166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.