Evidence map›Paper›PMID 40671479›Full record

ArticleJournal of cosmetic dermatology2025

Effects of a Ceramide-Containing Glycinate-Based Cleanser on the Condition of Oily Skin and Skin Post-IPL Treatments.

Yunqiu Xia, Yansi Lyu, Jiahong Yang, Xiaofeng He, Yi Yi, Jingjing Liu, Zailing Zhu, Zheng Du, Yuchao Chen, Yunfei Ai

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yunqiu XiaDepartment of Dermatology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Yansi LyuDepartment of Dermatology, Shenzhen University General Hospital, Shenzhen, China.ORCID https://orcid.org/0000-0001-7909-9290
Jiahong YangL'Oréal Dermatological Beauty China, CeraVe, Shanghai, China.
Xiaofeng HeL'Oréal China Research & Innovation, Shanghai, China.
Yi YiL'Oréal China Research & Innovation, Shanghai, China.
Jingjing LiuL'Oréal China Research & Innovation, Shanghai, China.
Zailing ZhuL'Oréal China Research & Innovation, Shanghai, China.
Zheng DuL'Oréal China Research & Innovation, Shanghai, China.
Yuchao ChenL'Oréal China Research & Innovation, Shanghai, China.
Yunfei AiL'Oréal Dermatological Beauty China, CeraVe, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently, many studies are exploring the effects of cleansers containing petrolatum and fatty acids on skin condition, but no research has yet investigated the impact of cleansers containing ceramides on skin condition.

aimsTherefore, this study aims to explore whether a ceramide-containing glycinate-based cleanser can improve the skin conditions of oily skin and skin post-intense pulsed light (IPL) treatments, with a particular focus on the skin barrier.

methodsIn this study, 88 volunteers were recruited and divided into two groups. Group 1 (n = 44, oily skin) used ceramide-containing cleansers for 28 days, with subsequent assessment of skin hydration, TEWL (transepidermal water loss), sebum content, and pore count. Group 2 (n = 44) received IPL treatment prior to using the same cleansers, followed by evaluation of redness and self-reported symptoms.

resultsThe experimental results demonstrated that in Group 1, after 28 days of product application, skin hydration increased by 47.37%, TEWL decreased by 13.42%, pore number was reduced by 6.92%, and sebum content showed a 79.18% reduction. For Group 2, comparative analysis revealed that following the use of ceramide-containing cleansers after IPL treatment, skin redness significantly decreased by 14.62% compared to post-IPL measurements, with concurrent notable improvements in all self-reported symptoms, including itching and tightness.

conclusionsOverall, a ceramide-containing glycinate-based cleanser can effectively control sebum secretion, reduce pore size, and repair the skin barrier in oily skin. Additionally, it can help reduce redness in IPL-treated skin. For dermatologists and consumers, this formulation represents a promising option for people undergoing IPL procedures, combining cleansing with barrier repair to minimize post-treatment downtime.

Indexed as

CeramidesDetergentsGlycineSkinAdultFemaleHumansMaleMiddle AgedSebumSkin CareWater Loss, InsensibleYoung AdultCeramidesDetergentsGlycineceramidescleansersskin function

Identifiers

PMID40671479
PMCPMC12268312

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.