Evidence map›Paper›PMID 40671420›Full record

ArticlePediatric pulmonology2025

Predischarge Betamethasone in Infants Diagnosed With Bronchopulmonary Dysplasia.

Tal-El Ernest, Doreen Ozalvo, Orna Staretz-Chacham, Kyla A Marks, Eilon Shany, Daniela Landau, Justin Richardson

Abstract read
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In one paragraph

Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tal-El ErnestNeonatal Department and Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beersheba, Israel.
Doreen OzalvoNeonatal Department and Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beersheba, Israel.
Orna Staretz-ChachamNeonatal Department and Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beersheba, Israel.
Kyla A MarksNeonatal Department and Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beersheba, Israel.
Eilon ShanyNeonatal Department and Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beersheba, Israel.ORCID https://orcid.org/0000-0003-4142-3707
Daniela LandauNeonatal Department and Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beersheba, Israel.
Justin RichardsonNeonatal Department and Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beersheba, Israel.

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

backgroundThe aim of this study was to assess the influence of a short betamethasone therapy course for infants diagnosed with BPD on the need of oxygen therapy after discharge home, on post-menstrual age (PMA) discharge, and on hospital readmission rates.

methodsThis was a retrospective cohort study that included infants born and diagnosed with BPD in the Soroka University Medical Center neonatal department between 2012 and 2020. Demographic and clinical parameters were extracted from computerized medical files.

resultsOverall, 187 infants were included in the study; 151 (81%) were treated with betamethasone, of them 110 (73%) were discharged home without supplemental oxygen. Nonsignificant differences were found between infants treated with or without betamethasone regarding home oxygen supplementation at discharge (27% treated vs. 17% without, p = 0.192) and PMA at discharge (40.2 weeks treated vs. 41.2 weeks not treated, p = 0.114). Of the infants receiving betamethasone, those weaned from oxygen were discharged home at an earlier PMA (39.6 ± 5.0 vs. 42.0 ± 3.7 week, p < 0.001) and there was no difference between readmission rates due to respiratory problems of infants discharged home without oxygen supplementation to those discharged with oxygen (37/108 [34%] vs. 14/36 [39%], p = 0.615). In multivariable analysis, respiratory support at 36 weeks PMA (odds ratio: 4.4 [CI: 1.5-13.2], p < 0.009) and receiving two or more courses of betamethasone (odds ratio: 3.6 [CI: 1.2-10.5], p = 0.009) were significant predictors for need of oxygen supplementation at discharge.

conclusionsUse of corticosteroids for infants diagnosed with BPD may shorten hospital stay by promoting weaning from oxygen therapy.

Indexed as

BetamethasoneBronchopulmonary DysplasiaGlucocorticoidsOxygen Inhalation TherapyFemaleHumansInfantInfant, NewbornMalePatient DischargePatient ReadmissionRetrospective StudiesBetamethasoneGlucocorticoids

Identifiers

PMID40671420
PMCPMC12268240

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.