SynthesisAnnals of medicine2025
The risk of dementia in breast cancer survivors: a meta-analysis of observational studies.
Synthesis in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Surgical Ovarian Suppression and Breast Cancer-What Do We Know About It?Medicina (Kaunas, Lithuania) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveCognitive problems are among the most common post-treatment symptoms experienced by breast cancer patients, raising concerns about their long-term cognitive health. This meta-analysis aims to clarify the relationship between cognitive decline in breast cancer survivors and the risk of developing dementia. MATERIALS AND
methodsPubMed, Embase, and Cochrane Library were searched for cohort studies published from database inception to August 27, 2024, using medical subject headings (MeSH) and keywords. All statistical analyses were performed using Stata statistical software version 14.0. If
resultsThe meta-analysis, comprising 9 studies and involving 887,678 individuals, revealed that breast cancer survivors did not exhibit an increased risk of all-cause dementia [RR = 0.997, 95%CI (0.965, 1.029); I
conclusionThis meta-analysis indicates that breast cancer survivors do not face an elevated risk of all-cause dementia. Furthermore, treatments such as endocrine therapy and chemotherapy may have a protective effect against dementia. Further research is needed to explore the underlying mechanisms and confirm these findings.
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Registered trials
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