Evidence map›Paper›PMID 40671315›Full record

ArticleJournal of evidence-based medicine2025

Validation of a Self-Assessment Tool for Osteoporosis and Vertebral Fracture Primary Screening in Elderly Men.

Li Shen, Chao Gao, Tianrui He, Liting Chu, Jie Wang, Zhenlin Zhang, Guangjun Yu

Abstract readValidation Study
In one paragraph

Article in Journal of evidence-based medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Li ShenClinical Research Center, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chao GaoShanghai Clinical Research Center of Bone Disease, Department of Osteoporosis and Bone Diseases, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tianrui HeZhongshan Hospital Institute of Clinical Science, Fudan University Shanghai Medical College, Shanghai, China.ORCID https://orcid.org/0000-0003-2754-2902
Liting ChuInstitute of Child and Adolescent Health, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Jie WangShanghai Clinical Research Center of Bone Disease, Department of Osteoporosis and Bone Diseases, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhenlin ZhangClinical Research Center, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Guangjun YuSchool of Medicine, The Chinese University of Hong Kong, Shenzhen, China.

Funding

Clinical Science and Technology, Whitechapel Foundation Project GX2021A02Fundamental Research Funds for the Central Universities YG2023QNB20Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital ynhg202210Training Program for Research Physicians in Innovation and Translation of Shanghai Hospital Development Center SHDC2023CRS039
6 · The paper itself

Abstract

objectiveThe early identification of osteoporosis and vertebral fractures (VFs) is vital for improving the quality of life in elderly men. This study aimed to validate the effectiveness of a self-assessment tool for osteoporosis and VFs primary screening in the elderly men.

methodsThis real-world study analyzed data from two sources: an electronic health record (EHR) database comprising 7187 subjects and a community database including 6313 subjects. Restricted cubic spline curves were utilized to analyze the relationship between the osteoporosis self-assessment tool for Asians (OSTA) index and the prevalence of osteoporosis, overall VFs, and moderate to severe VFs. Diagnostic performance was assessed by calculating sensitivity, specificity, and area under the receiver operating characteristic curve (AUC), and optimal cutoff values were determined for different age groups.

resultsWith a cutoff value of -1, the OSTA index demonstrated good diagnostic performance for identifying osteoporosis, achieving an AUC of 0.712 (p < 0.001), with sensitivity and specificity of 81.6% and 78.1%, respectively. The screening performance was notably higher among individuals aged 70-79 and those over 80 years, with AUCs of 0.79 and 0.81, respectively, and sensitivities exceeding 90%. For moderate to severe VFs, the OSTA index demonstrated a sensitivity of 86.6%, a specificity of 53.1%, and an AUC of 0.628.

conclusionsThis large-scale real-world study supports the utility of the OSTA index as a valid tool for the primary screening of osteoporosis and VFs in the elderly men.

Indexed as

Mass ScreeningOsteoporosisSelf-AssessmentSpinal FracturesAgedAged, 80 and overHumansMaleROC CurveSensitivity and Specificityelderly menosteoporosisosteoporosis self‐assessment tool for Asiansreal‐world studyvertebral fractures

Identifiers

PMID40671315
PMCPMC12506950

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.