Evidence map›Paper›PMID 40671229›Full record

ReviewCurrent stem cell research & therapy2026

Application of Artificial Intelligence in Stem Cells and Gene Therapy for Gynecological Cancers.

Shiva Gholizadeh-Ghaleh Aziz, Sakineh Aghazadeh, Anosha Malik, Amir Javed, Sania Shaheen, Laiba Naseem, Younas Sohail, Aliasghar Tabatabaei Mohammadi, Muhammad Farrukh Nisar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current stem cell research & therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. RNAi-mediated p38δ silencing mitigates anthracycline cardiotoxicity in female mice.American journal of physiology. Heart and circulatory physiology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shiva Gholizadeh-Ghaleh AzizCellular and Molecular Research Center, Cellular and Molecular Medicine Institute, Urmia University of Medical Sciences, Urmia, Iran.
Sakineh AghazadehDepartment of Education Development Center, Urmia University of Medical Sciences, Urmia, Iran.
Anosha MalikDepartment of Zoology, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur, 63100, Pakistan.
Amir JavedDepartment of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur, 63100, Pakistan.
Sania ShaheenDepartment of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur, 63100, Pakistan.
Laiba NaseemDepartment of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur, 63100, Pakistan.
Younas SohailDepartment of Biological and Environmental Sciences, Emerson University, Multan, Pakistan.
Aliasghar Tabatabaei MohammadiDepartment of Education Development Center, Urmia University of Medical Sciences, Urmia, Iran.
Muhammad Farrukh NisarDepartment of Physiology and Biochemistry, Cholistan University of Veterinary and Animal Sciences (CUVAS), Bahawalpur, 63100, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of artificial intelligence (AI) in stem cell and gene therapy offers significant advancements in the treatment of gynecological cancers, including breast, ovarian, and cervical cancers. This review explores how machine learning (ML) enhances both diagnostic and therapeutic strategies in regenerative medicine. AI integration allows for more accurate disease progression predictions, identification of therapeutic targets, and optimization of personalized treatment plans. Additionally, AI improves the efficacy and safety of stem cell and gene therapy approaches by facilitating the identification of biomarkers and genetic variations, enabling tailored therapies for individual patients. The use of AI-supported analytics in combined treatment strategies presents new avenues for effective cancer management. Furthermore, AI-driven regenerative medicine optimizes stem cell functions, refines treatment protocols, and contributes to the identification of less frequent biomarkers, improving prognostic algorithms and therapy outcomes. As ML targets specific molecular changes in cancer cells, they enhance the precision of gene silencing and anti-aging interventions, offering new possibilities for combined therapies. These innovations position AI as a transformative tool in the development of personalized and effective treatments for women's cancers, with future studies likely to expand the scope and impact of AI-driven strategies.

Indexed as

Artificial IntelligenceGenetic TherapyGenital Neoplasms, FemaleStem CellsStem Cell TransplantationAnimalsFemaleHumansMachine LearningPrecision MedicineRegenerative MedicineArtificial intelligencecancersgene therapygynecologymachine learningstem cell therapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.