Evidence map›Paper›PMID 40671177›Full record

ArticlePsycho-oncology2025

Psychosocial Interventions to Relieve Traumatic Stress Symptoms in Family Caregivers of Children With Cancer: A Scoping Review.

Stephanie M Nanos, Argin Malakian, Laura Foran, Elizaveta Klekovkina, Kyle P Fitzgibbon, Ally Yu, Angela Mathews, Gary Rodin, Lindsay A Jibb

Abstract readScoping Review
In one paragraph

Article in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. A dyadic approach to understanding anxiety and child overall health in pediatric oncology: insights from an actor-partner interdependence model.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stephanie M NanosUniversity of Toronto, Toronto, Canada.ORCID 0009-0009-5437-831X
Argin MalakianUniversity of Toronto, Toronto, Canada.
Laura ForanPrincess Margaret Cancer Centre, Toronto, Canada.
Elizaveta KlekovkinaPrincess Margaret Cancer Centre, Toronto, Canada.
Kyle P FitzgibbonPrincess Margaret Cancer Centre, Toronto, Canada.
Ally YuUniversity of Toronto, Toronto, Canada.
Angela MathewsUniversity of Toronto, Toronto, Canada.
Gary RodinUniversity of Toronto, Toronto, Canada.
Lindsay A JibbUniversity of Toronto, Toronto, Canada.ORCID 0000-0001-6995-2825

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraumatic stress symptoms are common, severe, and persistent in family caregivers of children with cancer, but the benefits of therapeutic interventions to relieve them are not well established.

aimTo review, describe, and appraise the available research on psychosocial interventions aimed at alleviating traumatic stress symptoms in family caregivers of children with cancer.

methodsSystematic searches of APA PsycInfo, CINAHL, MEDLINE, and Embase were conducted to identify randomized controlled trials (RCTs) and nonrandomized studies of psychosocial interventions (NRSIs) for families affected by pediatric cancer in which traumatic stress symptoms were reported as a primary or secondary outcome. Results were screened by independent reviewers in duplicate. 18 articles were included. All were evaluated for risk of bias and data on study design, intervention format, delivery, and impact, and were abstracted for narrative synthesis.

resultsStudy samples (8-430 participants) were primarily comprised of mothers of children with acute leukemia. Most interventions (1 day-15 weeks) involved an interventionist (n = 17; 94%) and used cognitive-behavioral techniques (n = 14; 78%). Eight RCTs (n = 10; 80%) and seven NRSIs (n = 8; 87.5%) found a significant reduction in traumatic stress symptoms following intervention delivery, with small to large effect sizes (Cohen's d = 0.28-1.30). However, only three RCTs confirmed having adequate power to comment on effectiveness. Risk of bias ranged from low to moderate.

conclusionsThe prevalence and problematic nature of traumatic stress symptoms in this population is well documented in the observational literature. However, the evidence remains unclear as to the effectiveness of psychosocial interventions to alleviate them due to methodological limitations in current interventional research. High quality RCTs that include a diverse group of family caregivers are needed to demonstrate their effectiveness and to inform clinical care practices aimed at improving family wellbeing.

Indexed as

CaregiversFamilyNeoplasmsPsychosocial InterventionStress, PsychologicalChildCognitive Behavioral TherapyHumanscancercaregiversoncologypalliative careparentspediatric oncologypsychosocial interventionscoping reviewtraumatic stress disorders

Identifiers

PMID40671177
PMCPMC12267684

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.