Evidence map›Paper›PMID 40671127›Full record

ArticleImplementation science communications2025

Lessons from using the Normalisation Process Theory to understand adherence to guidance on MgSO

Christalla Pithara-McKeown, Tracey Stone, Emma Treloar, Jenny Donovan, Karen Luyt, Sabi Redwood

Abstract read
In one paragraph

Article in Implementation science communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christalla Pithara-McKeownThe National Institute for Health and Care Research Applied Research Collaboration West (NIHR ARC West) at University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK. c.pithara-mckeown@bristol.ac.uk.ORCID http://orcid.org/0000-0003-2958-5201
Tracey StoneThe National Institute for Health and Care Research Applied Research Collaboration West (NIHR ARC West) at University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Emma TreloarUniversity Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Jenny DonovanBristol Medical School, Population Health Sciences, University of Bristol, Bristol, UK.
Karen LuytThe National Institute for Health and Care Research Applied Research Collaboration West (NIHR ARC West) at University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Sabi RedwoodThe National Institute for Health and Care Research Applied Research Collaboration West (NIHR ARC West) at University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.

Funding

National Institute for Health Research Applied Research Collaboration West NIHR200181The Health Foundation (UK) 557668
6 · The paper itself

Abstract

backgroundThe administration of magnesium sulphate (MgSO

methodsRemote semi-structured interviews were carried out as part of an evaluation of (1) the PReCePT (Preventing Cerebral Palsy in Pre-Term Labour) National Programme, and (2) the PReCePT cRCT study, and as part of a qualitative study investigating MgSO

resultsInterviews with 86 strategic and clinical leads and implementers from the three nations suggested that despite evidence being necessary and important for policy decision-making and clinical buy-in, improvement interventions were motivated by audit data and benchmarking. Scaling of improvement was driven by knowledge sharing, diffusion of innovation, and capacity building through relational structures (e.g. networks, communities) spanning the perinatal ecosystem. Local champions operating in multiple communities and networks as boundary-spanners connected national and regional leadership, patient group representatives, implementers i.e. clinical leads and champions, and perinatal clinical teams to enable knowledge mobilisation. Their work relied on backfill funding and protected time, and social-cognitive and social-structural resources in their settings. Sense-making, cognitive participation, collective action and reflexive monitoring work took place iteratively and dynamically within and across these structures on each level of the system.

conclusionsQI interventions driven by knowledge mobilisation can drive scaling and spreading of improvement, but require knowledge sharing and an infrastructure within the system to support improvement capacity building. Strong leadership with the ability to address power imbalances between co-actors, and secure protected funding for local champions is also required.

Indexed as

Evidence-based guidelinesKnowledge mobilisationMagnesium sulphateNormalisation process theoryPreterm labourQuality improvement

Identifiers

PMID40671127
PMCPMC12265282

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.