Evidence map›Paper›PMID 40671103›Full record

ArticleChild and adolescent psychiatry and mental health2025

BRAVA: A randomized controlled trial of a brief group intervention for youth with suicidal ideation and their caregivers.

Allison Kennedy, Clare Gray, Nicole Sheridan, Leigh Dunn, Jayme Stewart, Stéphanie Drouin, Hannah Elliott, Ademola Adeponle, Nicholas Barrowman, Ewa Sucha and 4 more

Registry-linked trialAbstract read
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In one paragraph

Article in Child and adolescent psychiatry and mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04751968 (Building Resilience and Attachment in Vulnerable Adolescents), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04751968 nacompletednot on this map

Building Resilience and Attachment in Vulnerable Adolescents (BRAVA): A Randomized Controlled Trial of a Brief Group Intervention for Adolescents With Mild to Moderate Suicidal Ideation and Their Caregivers

TypeinterventionalSponsorChildren's Hospital of Eastern OntarioRan2021 to 2023Enrolled99ConditionsSuicidal Ideation, Suicide and Self-harmArmsGroup Intervention, Enhanced Treatment as Usual
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Allison KennedyChildren's Hospital of Eastern Ontario (CHEO), 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.ORCID http://orcid.org/0000-0002-4090-4288
Clare GrayChildren's Hospital of Eastern Ontario (CHEO), 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.
Nicole SheridanCHEO Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.ORCID https://orcid.org/0000-0003-1894-8417
Leigh DunnCHEO Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.ORCID https://orcid.org/0000-0002-3589-4687
Jayme StewartCHEO Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.ORCID https://orcid.org/0000-0003-0383-4388
Stéphanie DrouinCHEO Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.ORCID https://orcid.org/0000-0003-4697-089X
Hannah ElliottChildren's Hospital of Eastern Ontario (CHEO), 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.
Ademola AdeponleChildren's Hospital of Eastern Ontario (CHEO), 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.ORCID https://orcid.org/0000-0001-5947-492X
Nicholas BarrowmanCHEO Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.ORCID https://orcid.org/0000-0002-4704-9595
Ewa SuchaCHEO Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.
Mario CappelliCHEO Research Institute, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.
Mark L NorrisChildren's Hospital of Eastern Ontario (CHEO), 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.ORCID https://orcid.org/0000-0002-6651-5803
Mona JabbourChildren's Hospital of Eastern Ontario (CHEO), 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.
Paula CloutierChildren's Hospital of Eastern Ontario (CHEO), 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada. pcloutier@cheo.on.ca.ORCID http://orcid.org/0000-0003-3095-1942

Funding

CHEO Psychiatry Associates n/aCHEO Research Institute n/aMach-Gaensslen Foundation of Canada n/a
6 · The paper itself

Abstract

objectivesSuicide is the second leading cause of mortality among Canadian youth. As wait times for mental health (MH) support have increased, adolescents with mild-to-moderate suicidal ideation (SI) are waiting longer for support compared to those with more acute SI. Building Resilience and Attachment in Vulnerable Adolescents (BRAVA) is a 6-week virtual group intervention designed to provide support to adolescents with mild to moderate SI and their caregivers. We conducted a randomized controlled trial to assess the efficacy of BRAVA in reducing symptoms of SI, depression, and anxiety in adolescents, and improving life stress in caregivers. DESIGN/

methodsOutcome measures were administered to both groups [BRAVA, Enhanced Treatment-as-Usual (ETU)] at intake and exit, and at 3-month follow-up (BRAVA only) for SI (primary outcome), anxiety and depression (adolescent), perceived stress (youth and caregiver), attachment and family functioning (caregiver). SI was measured using Suicidal Ideation Questionnaire Junior. Intention to treat (ITT) analysis was performed for youth and caregiver cohorts.

resultsNinety-nine eligible youth presenting with mild-to-moderate SI and their caregivers were recruited from hospital and community MH services. Families were randomized to BRAVA (n = 50) or ETU (n = 49). Adolescents were on average 14.6 years old, mostly female (64%), and of European racial heritage (44%). In ITT analysis, both BRAVA and ETU groups improved in youth SI from intake to exit, with no statistically significant differences between groups at exit. Sensitivity analysis without multiple imputations demonstrated a significant difference in SI scores at exit between the groups, where improvements in the BRAVA group were maintained at 3-month follow-up. Significant differences between groups on youth perceived stress, and depression and anxiety scores were also observed in BRAVA participants at post-treatment compared to the ETU control group. No statistically significant differences were observed for any caregiver outcomes measured except a trend for improved perceived caregiver stress in the BRAVA group post-treatment.

conclusionsBRAVA was associated with significantly greater improvements in anxiety/depression and adolescent perceived stress compared to ETU. Although the intervention did not result in significant caregiver reported improvements, group cohesion and treatment satisfaction were high for both youth and caregivers. CLINICAL

trial registrationBRAVA: Building Resilience and Attachment in Vulnerable Adolescents (BRAVA); https://clinicaltrials.gov/ : NCT04751968.

Indexed as

AdolescentsCaregiversEffectiveness studyRandomized controlled trialSuicidal ideationTreatment

Identifiers

PMID40671103
PMCPMC12265114

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.