Evidence map›Paper›PMID 40671081›Full record

ArticleHereditas2025

Delving into the pinnacle: an in-depth analysis of the top 100 most cited articles on cardio-oncology.

Ping Lai, Shuquan Xu, Zi-Xuan Cao, Zi-You Liu, Ke-Jun Tian, Wen-Ting Zhong, Xia Liu, Yi-Ming Zhong, Xiao-Ping Wang, Jin-Hua Xue

Abstract read
In one paragraph

Article in Hereditas, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ping Lai *Department of Cardiology, The First Affiliated Hospital of Gannan Medical University, Gannan Medical University, Ganzhou, Jiangxi Province, 341000, China.
Shuquan Xu *The First School of Clinical Medicine, Gannan Medical University, Ganzhou, Jiangxi Province, 341000, China.
Zi-Xuan Cao *Heze Central Blood Station, Heze, Shandong Province, 274000, China.
Zi-You LiuHeart Medical Centre, First Affiliated Hospital of Gannan Medical University, Ganzhou, Jiangxi Province, 341000, China.
Ke-Jun TianDepartment of Cardiology, The First Affiliated Hospital of Gannan Medical University, Gannan Medical University, Ganzhou, Jiangxi Province, 341000, China.
Wen-Ting ZhongDepartment of Cardiology, The First Affiliated Hospital of Gannan Medical University, Gannan Medical University, Ganzhou, Jiangxi Province, 341000, China.
Xia LiuDepartment of Oncology, The First Affiliated Hospital of Gannan Medical University, Gannan Medical University, Ganzhou, Jiangxi Province, 341000, China.
Yi-Ming ZhongDepartment of Cardiology, The First Affiliated Hospital of Gannan Medical University, Gannan Medical University, Ganzhou, Jiangxi Province, 341000, China.
Xiao-Ping WangDepartment of Cardiology, The First Affiliated Hospital of Gannan Medical University, Gannan Medical University, Ganzhou, Jiangxi Province, 341000, China. wxping@gmu.edu.cn.
Jin-Hua XueKey Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou, 341000, China. xjhua@gmu.edu.cn.

Funding

Talents' Start-up Foundation of Gannan Medical University QD202014The National Public Fund for Study Abroad and CSC scholarship NO. 202008360179The Natural Science Foundation of Jiangxi Province 20212BAB206001
6 · The paper itself

Abstract

The intersection of myocardial diseases and cancer therapy-induced cardiovascular toxicity has garnered significant attention in recent years. As the field of cardio-oncology bridges cardiology and oncology, research is expanding rapidly. This study analyzes the top 100 most cited papers (T100) in cardio-oncology, providing valuable insights into current trends and key research areas. Using Microsoft Excel 2009, we conducted a comprehensive temporal analysis of publications and citations. To visualize complex networks involving co-citations, countries, and author keywords, we utilized VOSviewer software. Additionally, Citespace was employed to identify clusters of keywords experiencing notable citation surges. The T100 selection includes 81 clinical research papers and 19 foundational studies. Key journals such as the European Heart Journal and the Journal of the American College of Cardiology stand out, collectively accumulating over 700 citations (9 papers from European Heart Journal and 7 from Journal of the American College of Cardiology). Notably, the United States leads the field with 41 publications and 2,868 citations, excluding self-citations. Prominent keywords emerging in this area include “cardiovascular diseases” (strength 2.48, 2019–2022), “management” (average publication year: September 2019, occurrence: 11 times), and “immune checkpoint inhibitors” (average publication year: 2020, occurrence: 5 times). While the T100 predominantly comprises clinical research, there is a discernible gap in foundational studies exploring the mechanisms of myocardial diseases induced by cancer therapy-related cardiovascular toxicity. The USA continues to dominate this field. Research in cardio-oncology focuses on cardiovascular diseases, especially heart failure and atrial fibrillation, with an emphasis on comprehensive management strategies and the potential of immune checkpoint inhibitors. This study offers valuable insights that could enhance our understanding and management of cardio-oncological complications.

Indexed as

BibliometricsCardio-OncologyCardiovascular DiseasesHumansJournal Impact FactorNeoplasmsPeriodicals as TopicCardio-oncologyCitespaceManagementMost citedVOSviewer

Identifiers

PMID40671081
PMCPMC12269302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.