Evidence map›Paper›PMID 40671046›Full record

ReviewCancer cell international2025

Medicinal plants: nutritional, immunological and therapeutic role in treating cancer-related malnutrition: a comprehensive review.

Mohamed T El-Saadony, Samar Sami Alkafaas, Ahmed M Saad, Dina Mostafa Mohammed, Sameh A Korma, Heba M Salem, Taia A Abd El-Mageed, Mohamed I Elsalahaty, Sara Samy Elkafas, Walid F A Mosa and 12 more

Abstract readReview
In one paragraph

Review in Cancer cell international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Suppressive Potential of Ethanolic Extracts ofInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Anti-Metastatic Effects ofInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Mohamed T El-SaadonyDepartment of Agricultural Microbiology, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt. m.talaatelsadony@gmail.com.
Samar Sami AlkafaasMolecular Cell Biology Unit, Division of Biochemistry, Department of Chemistry, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
Ahmed M SaadDepartment of Biochemistry, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt.
Dina Mostafa MohammedNutrition and Food Sciences Department, National Research Centre, Dokki, Giza, 12622, Egypt.
Sameh A KormaDepartment of Food Science, Faculty of Agriculture, Zagazig University, Zagazig, 44519, Egypt.
Heba M SalemDepartment of Poultry Diseases, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Taia A Abd El-MageedDepartment of Soils and Water, Faculty of Agriculture, Fayoum University, Fayoum, 63514, Egypt.
Mohamed I ElsalahatyMolecular Cell Biology Unit, Division of Biochemistry, Department of Chemistry, Faculty of Science, Tanta University, Tanta, 31527, Egypt.
Sara Samy ElkafasProduction Engineering and Mechanical Design Department, Faculty of Engineering, Menofia University, Menofia, 32511, Egypt.
Walid F A MosaPlant Production Department (Horticulture-Pomology), Faculty of Agriculture Saba Basha, Alexandria University, Alexandria, 21526, Egypt.
Ahmed Ezzat AhmedBiology Department, College of Science, King Khalid University, Abha, 61413, Saudi Arabia.
Essam H IbrahimBiology Department, College of Science, King Khalid University, Abha, 61413, Saudi Arabia.
Fawze AlnadariResearch and Development Center, Jiangsu Tianmeijian Nature Bioengineering Co., Ltd., Nanjing, 210046, China.
Betty T MathewDepartment of Biology, College of Science, United Arab Emirates University, Al Ain, 15551, United Arab Emirates.
Alaa S AbdelhamidDepartment of Nutrition and Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, 15551, United Arab Emirates.
Sahar F AllabanDepartment of Chemistry, College of Science, United Arab Emirates University, Al Ain, 15551, United Arab Emirates.
Samah A LoutfyVirology and Immunology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt.
Soumya GhoshNatural and Medical Sciences Research Center, University of Nizwa, Nizwa, 616, Oman.
Hanya Y AssalFaculty of Biotechnology, October University for Modern Sciences and Arts, 6th October City, 12451, Egypt.
Marawan K El-TarabilyFaculty of Medicine, University of Debrecen, Debrecen, 4032, Hungary.
Synan F AbuQamarDepartment of Biology, College of Science, United Arab Emirates University, Al Ain, 15551, United Arab Emirates.
Khaled A El-TarabilyDepartment of Biology, College of Science, United Arab Emirates University, Al Ain, 15551, United Arab Emirates. ktarabily@uaeu.ac.ae.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is the second leading cause of death globally, following microbial infection, with an estimated 16 million deaths projected by 2040. However, natural resources can potentially treat up to 60% of cancer cases. Various cancers, including those affecting the breast, prostate, stomach, colon, lung, liver, kidney, bone, skin, and blood, have strong dietary connections regarding their occurrence and prevention. Cancer and its treatments, particularly chemotherapy, are closely associated with malnutrition in humans. The adverse effects of medical therapies and the disease itself often prevent patients with cancer from meeting their nutritional needs through regular food intake. The etiology of malnutrition in patients with cancer is complex and multifactorial, influenced by the type and location of cancer, disease stage, side effects of treatment, economic status, functional capacity, symptoms impacting nutrition, fasting requirements, inadequate dietary therapy, and awareness of the clinical staff regarding the role of dietary habits in diagnosis, treatment, and quality of life. Although there have been advances in drug-targeted therapies, they remain unelucidated, and therefore, this review aims to elucidate the relationship between cancer, chemical treatments, and malnutrition. In addition, it highlights the significant role of medicinal plants in treating various cancers and mitigating the adverse side effects of chemotherapy, offering a comprehensive understanding of their nutritional, immunological, and therapeutic benefits.

Indexed as

CancerChemotherapyClinical nutritionDietary intakeDrugsMedicinal herbs

Identifiers

PMID40671046
PMCPMC12269176

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.