Evidence map›Paper›PMID 40671005›Full record

ReviewBMC ophthalmology2025

Multiple evanescent white dot syndrome associated with focal scleral nodule: a case report and literature review.

Abdulla Sawut, Yang Meng, Tsering Lhamo, Di Xiao, Yu Su, Changzheng Chen

Abstract readCase ReportsReview
In one paragraph

Review in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abdulla Sawut *Eye Center, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan, 430060, China.
Yang Meng *Eye Center, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan, 430060, China.
Tsering LhamoEye Center, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan, 430060, China.
Di XiaoEye Center, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan, 430060, China.
Yu SuEye Center, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan, 430060, China. sy_daisy1206@163.com.
Changzheng ChenEye Center, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan, 430060, China. whuchenchzh@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple evanescent white dot syndrome (MEWDS) is a rare transient inflammatory retinopathy characterized by discrete white dots disseminated on the fundus. Focal scleral nodule (FSN) typically presents as a stable, solitary, yellow-white, subretinal lesion arising from the sclera. This article reports a rare case of MEWDS associated with FSN in a young female. CASE PRESENTATION: A 34-year-old female presented with a complaint of gradually enlarging paracentral scotomas in the left eye for 8 days. At presentation, best-corrected visual acuity (BCVA) was 20/25 in the left eye. Fundus examination of the left eye revealed optic disc edema and an orange-yellow irregular lesion on the infratemporal side of the fovea. The multimodal imaging (MMI) findings revealed a rather typical MEWDS-like reaction and a subretinal lesion located at the sclera. After thorough consideration, the patient was diagnosed with MEWDS associated with FSN. Corticosteroid therapy was then administered to the patient. After 11 weeks, her BCVA recovered to 20/20 in the left eye, and the visual field defect had improved. Additionally, the MEWDS-like reaction had significantly recovered. The FSN remained stable during the 18-month follow-up.

conclusionsThis is the first reported case of MEWDS associated with FSN, expanding the understanding of both conditions.

Indexed as

Retinal DiseasesScleraScleral DiseasesWhite Dot SyndromesAdultFemaleFluorescein AngiographyFundus OculiHumansTomography, Optical CoherenceVisual AcuityCase reportFocal scleral noduleMEWDS-like reactionMultiple evanescent white Dot syndromeReviewSecondary MEWDS

Identifiers

PMID40671005
PMCPMC12265223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.