ArticleBMC surgery2025
Comparison of the effects of laparoscopic sleeve gastrectomy and endoscopic intragastric balloon placement on hormone profile and menstrual cycle in obese women with polycystic ovary syndrome.
Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bariatric surgery as a treatment of polycystic ovary syndrome: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Endoscopic Versus Surgical Bariatric Interventions for Obesity: A Systematic Review and Network Meta-Analysis.Journal of clinical medicine research · 2026Article
- The Management of Polycystic Ovary Syndrome in Adolescents with Obesity.Advances in therapy · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimObesity is a significant public health problem with increasing prevalence worldwide, and polycystic ovary syndrome (PCOS) is a common comorbidity in obese women. PCOS is characterized by hormonal imbalances, menstrual irregularities, infertility, and metabolic disorders. Weight management is critical in obese women with PCOS to improve both reproductive health and achieve metabolic and hormonal balance. To this end, surgical treatments have come to the forefront, and procedures such as laparoscopic sleeve gastrectomy (LSG) and endoscopic intragastric balloon (EIB) placement are being used increasingly. METHODS AND
resultsThis is a retrospective study conducted at [Blinded for review] between January 2022 and October 2024. It compares the effects of laparoscopic sleeve gastrectomy and endoscopic intragastric balloon placement in female patients aged 18-40 who were diagnosed with PCOS and obesity. In the study, anthropometric measurements, hormonal parameters, and menstrual cycles were evaluated before treatment and 6 months after treatment and analyzed between the two groups. There was no difference in age between patients who underwent laparoscopic sleeve gastrectomy and endoscopic intragastric balloon placement (p = 0.424). The preoperative BMI and the difference between preoperative and postoperative BMI were higher in the LSG group (p < 0.001), but the postoperative BMI values were similar between the two groups (p = 0.583). The waist/hip ratio was higher in the LSG group (p < 0.001, p = 0.010, p < 0.001). While both surgeries showed a reduction in free androgen index and AMH, this reduction was not statistically significant (p > 0.05), both surgeries increased SHBG (p > 0.05). The decrease in AMH was greater in the LSG group (p = 0.020). Total testosterone decreased in the sleeve gastrectomy group (p < 0.001) and the menstrual cycle improved (p = 0.035).
conclusionIn summary, both laparoscopic sleeve gastrectomy and endoscopic intragastric balloon placement led to positive changes in hormone profiles and menstrual cycle characteristics. However, LSG was found to be more effective on these parameters.
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