Development of a laboratory-based frailty index for risk prediction in elderly trauma patients with hip fractures.

Malou-Sophie Dietrich, Emmanouil Liodakis, Stephan Sehmisch, Marcel Winkelmann, Manfred Gogol

Abstract read

In one paragraph

Article in GeroScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Development and internal validation of prediction model for 90-day mortality in older patients with hip fracture using admission blood parameters.BMC geriatrics · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Malou-Sophie DietrichDepartment of Trauma Surgery, Hannover Medical School, Carl-Neuberg-Straße 1, Hannover, 30625, Germany. dietrich.malou-sophie@mh-hannover.de.

Emmanouil LiodakisDepartment of Trauma Surgery, Hannover Medical School, Hannover, Lower Saxony, Germany.

Stephan SehmischDepartment of Trauma Surgery, Hannover Medical School, Hannover, Lower Saxony, Germany.

Marcel WinkelmannDepartment of Trauma Surgery, Hannover Medical School, Hannover, Lower Saxony, Germany.

Manfred GogolDepartment of Trauma Surgery, Hannover Medical School, Hannover, Lower Saxony, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to develop a laboratory-based frailty index (FI-Lab) to predict 12-month mortality risk in elderly patients following a hip fracture (HF). A retrospective analysis of 235 consecutive patients over 70 years old, who underwent HF surgery, was conducted. The FI-Lab, based on 21 routine blood parameters, was evaluated using Receiver Operating Characteristics, Area Under the Curve (AUC), Kaplan-Meier curves, and Cox proportional Hazard ratios. The FI-Lab showed an AUC of 0.7177 for 6-month and 0.7423 for 1-year survival. High FI-Lab values correlated with higher preoperative ASA scores, longer time-to-surgery times, more perioperative transfusions, and higher postoperative complication rates. The Cox hazard ratio revealed a significant increase in the risk of death for 1 year and 6 months from a score of 0.4 and higher. These findings highlight the FI-Lab's clinical relevance and validity as a predictive tool, emphasizing the need for differentiated perioperative risk stratification.

Indexed as

Frail ElderlyFrailtyHip FracturesAgedAged, 80 and overFemaleGeriatric AssessmentHumansKaplan-Meier EstimateMalePostoperative ComplicationsProportional Hazards ModelsRetrospective StudiesRisk AssessmentROC CurveHip fractureLaboratory-based frailty indexPredictive tool

Identifiers

PMID40670810

DOI10.1007/s11357-025-01789-1

PMCPMC12972344

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.