Evidence map›Paper›PMID 40670792›Full record

ArticleNature2025

Functional regimes define soil microbiome response to environmental change.

Kiseok Keith Lee, Siqi Liu, Kyle Crocker, Jocelyn Wang, David R Huggins, Mikhail Tikhonov, Madhav Mani, Seppe Kuehn

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. The ecological context of enzymatic variation.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Global epistasis in ecosystems arises from resource constraints.bioRxiv : the preprint server for biology · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Learning functional groups in complex microbiomes.bioRxiv : the preprint server for biology · 2026
    Article
  12. Microbial biotechnology meets ecological theory: a unified framework to design industrial microbial consortia.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Kiseok Keith Lee *Department of Ecology and Evolution, The University of Chicago, Chicago, IL, USA.ORCID 0000-0002-3298-7116
Siqi Liu *Department of Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, IL, USA.ORCID 0009-0005-1651-4713
Kyle CrockerDepartment of Ecology and Evolution, The University of Chicago, Chicago, IL, USA.ORCID 0000-0003-0531-1521
Jocelyn WangDepartment of Ecology and Evolution, The University of Chicago, Chicago, IL, USA.
David R HugginsUSDA-ARS, Northwest Sustainable Agroecosystems Research Unit, Pullman, WA, USA.
Mikhail TikhonovDepartment of Physics, Washington University in St Louis, St Louis, MO, USA. tikhonov@wustl.edu.ORCID 0000-0002-9558-1121
Madhav ManiCenter for Living Systems, The University of Chicago, Chicago, IL, USA. madhav.mani@gmail.com.ORCID 0000-0002-5812-4167
Seppe KuehnDepartment of Ecology and Evolution, The University of Chicago, Chicago, IL, USA. seppe.kuehn@gmail.com.ORCID 0000-0002-4130-6845

Funding

Environmental modulation of metabolic function in microbial communitiesR01GM151538 · NIGMS · UNIVERSITY OF CHICAGO · PI Seppe Kuehn · 2023 to 2026
$1.5M
NIGMS NIH HHS R01 GM151538
6 · The paper itself

Abstract

The metabolic activity of soil microbiomes has a central role in global nutrient cycles

Indexed as

Climate ChangeMicrobiotaSoilSoil MicrobiologyBacteriaBiomassHydrogen-Ion ConcentrationModels, BiologicalNitratesNutrientsNitratesNutrientsSoil

Identifiers

PMID40670792
PMCPMC12390847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.