ArticleNature2025
A male-essential miRNA is key for avian sex chromosome dosage compensation.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Screening and identification of genes for cell autonomous sex identity in chicken somatic cells.Poultry science · 2026Article
- Mixed Evidence that Dosage Sensitive Genes Drive Global Dosage Compensation in Flour Beetles.Genome biology and evolution · 2026Article
- Advances in Poultry RNA-Omics Research: Technologies, RNA Information Layers, and Applications in Complex Traits.Animals : an open access journal from MDPI · 2026Review
- The chicken retrovirus-like geneiScience · 2026Article
- High genotoxicity of CRISPR/Cas9 versus limited efficacy of CRISPRi in chicken primordial germ cells.Poultry science · 2026Article
- Manipulating primordial germ cells from chicken and other bird species.The Journal of reproduction and development · 2026Review
- In Vitro Culture of Avian Primordial Germ Cells: Established Methods and Future Directions.Biology · 2025Review
- Parallel Evolution of X Chromosome-Specific Structural Maintenance of Chromosomes Complexes in Two Nematode Lineages.Molecular biology and evolution · 2025Article
- Convergent evolution of H4K16ac-mediated dosage compensation in the ZW species Artemia franciscana.PLoS genetics · 2025Article
- Genome Editing in the Chicken: From PGC-Mediated Germline Transmission to Advanced Applications.International journal of molecular sciences · 2025Review
- Strain-specific variations in the culture of chicken primordial germ cells.Scientific reports · 2025Article
- microRNA as an Important Mediator in the Regulation of MaleInternational journal of molecular sciences · 2024Review
- Compensation of gene dosage on the mammalian X.Development (Cambridge, England) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Amir Fallahshahroudi *Center for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany. amirshahroudi@gmail.com.ORCID 0000-0001-8820-0098
Sara Yousefi Taemeh *Department of Medical Biochemistry and Microbiology, Biomedical Center (BMC), Uppsala University, Uppsala, Sweden.ORCID 0000-0001-7744-3414
Leticia Rodríguez-MontesCenter for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany.ORCID 0009-0002-6192-8497
Nils TrostCenter for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany.ORCID 0000-0002-5171-018X
Dana FrankCenter for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany.
Pascal LafrenzCenter for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany.ORCID 0000-0002-3791-3474
Jiri KoubekCenter for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany.
Guillermo TellezThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Maeve BallantyneThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Alewo Idoko-AkohSchool of Biochemistry, Faculty of Life Sciences, University of Bristol, Bristol, UK.
Lorna TaylorThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Adrian ShermanThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.
Megan DaveyThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.ORCID 0000-0003-0194-9229
Cheng MaDepartment of Medical Biochemistry and Microbiology, Biomedical Center (BMC), Uppsala University, Uppsala, Sweden.
Enrico SoratoReneco International Wildlife Consultants, Abu Dhabi, United Arab Emirates.
Martin JohnssonDepartment of Animal Biosciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Christina GrozouDepartment of Medical Biochemistry and Microbiology, Biomedical Center (BMC), Uppsala University, Uppsala, Sweden.
Ying XueCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Long LiuCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Guenter KramerCenter for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany.ORCID 0000-0001-7552-8393
Carl-Johan RubinDepartment of Medical Biochemistry and Microbiology, Biomedical Center (BMC), Uppsala University, Uppsala, Sweden.ORCID 0000-0001-8238-5052
Margarida Cardoso-MoreiraEvolutionary Developmental Biology Laboratory, Francis Crick Institute, London, UK.ORCID 0000-0001-6639-3597
Mike J McGrewThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK. mike.mcgrew@roslin.ed.ac.uk.ORCID 0000-0001-8213-4632
Henrik KaessmannCenter for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, Heidelberg University, Heidelberg, Germany. h.kaessmann@zmbh.uni-heidelberg.de.ORCID 0000-0001-7563-839X
Funding
BBSRC Core CapabilitiesEuropean Research CouncilFrancis Crick InstituteWellcome Trust CC2185
Abstract
Birds have a sex chromosome system in which females are heterogametic (ZW) and males are homogametic (ZZ)
Indexed as
ChickensDosage Compensation, GeneticGenes, EssentialMicroRNAsSex ChromosomesAnimalsChick EmbryoEvolution, MolecularFemaleGene Knockout TechniquesMaleProtein BiosynthesisTranscription, GeneticUp-RegulationMicroRNAs
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.