Evidence map›Paper›PMID 40670755›Full record

ArticleEcotoxicology (London, England)2025

The effects of multi-generational exposure to Fluorine-Free Foam (F3) alternatives on Daphnia magna tolerance.

Jack D Morehouse, Devin K Jones, Jason T Hoverman

Abstract read
In one paragraph

Article in Ecotoxicology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jack D MorehousePurdue University, Department of Biological Sciences, West Lafayette, IN, USA. jdmore8802@gmail.com.
Devin K JonesPurdue University, Department of Forestry and Natural Resources, West Lafayette, IN, USA.
Jason T HovermanPurdue University, Department of Forestry and Natural Resources, West Lafayette, IN, USA.

Funding

Strategic Environmental Research and Development Program ER20-1537 JTH
6 · The paper itself

Abstract

Per- and polyfluoroalkyl substances (PFAS) have historically been a key component in aqueous film-forming foams (AFFF) used in fire suppression. With the increasing emphasis on phasing out PFAS use due to health and environmental concerns, several new chemical technologies have been used to create fluorine-free foam (F3) alternatives. Recent research has demonstrated that these replacement formulations are more acutely toxic to aquatic species than the traditional PFAS-containing AFFF. Given their relatively high acute toxicity, prolonged exposure to the formulations could lead to adaptive responses (i.e., evolved tolerance) in exposed populations. In this study, we examined the effects of chronic exposure to six F3 alternatives and one PFAS-containing AFFF on tolerance to the formulations in the water flea Daphnia magna. Following an 84-day exposure to different concentrations of each formulation, we used a series of laboratory lethal concentration (LC

Indexed as

DaphniaFluorocarbonsWater Pollutants, ChemicalAnimalsDaphnia magnaFluorocarbonsWater Pollutants, ChemicalAdaptationContaminants of concernNon-monotonic responseSublethal effects

Identifiers

PMID40670755
PMCPMC12476401

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.