Evidence map›Paper›PMID 40670700›Full record

ArticleApplied microbiology and biotechnology2025

Development of a chemotactic SynCom bioorganic fertilizer for biocontrol of bacterial wilt in tobacco fields.

Yanxia Liu, Weiqi Zhang, Li Guo, Han Li, Jingwei Zhu, Xiang Li, Xiaoni Zhang, Xinrun Yang, Yangchun Xu, Qirong Shen and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yanxia Liu *Guizhou Academy of Tobacco Science, Guiyang, 550081, China.
Weiqi Zhang *Jiangsu Provincial Key Lab for Solid Organic Waste Utilization, Key Lab of Organic-based Fertilizers of China, Jiangsu Collaborative Innovation Center for Solid Organic Wastes, Educational Ministry Engineering Center of Resource-saving fertilizers, Nanjing Agricultural University, Nanjing, 210095, China.
Li GuoJiangsu Provincial Key Lab for Solid Organic Waste Utilization, Key Lab of Organic-based Fertilizers of China, Jiangsu Collaborative Innovation Center for Solid Organic Wastes, Educational Ministry Engineering Center of Resource-saving fertilizers, Nanjing Agricultural University, Nanjing, 210095, China.
Han LiGuizhou Academy of Tobacco Science, Guiyang, 550081, China.
Jingwei ZhuGuizhou Academy of Tobacco Science, Guiyang, 550081, China.
Xiang LiGuizhou Tobacco Corporation of CNTC, Guiyang, 550003, China. newcool1361214@163.com.
Xiaoni ZhangJiangsu Provincial Key Lab for Solid Organic Waste Utilization, Key Lab of Organic-based Fertilizers of China, Jiangsu Collaborative Innovation Center for Solid Organic Wastes, Educational Ministry Engineering Center of Resource-saving fertilizers, Nanjing Agricultural University, Nanjing, 210095, China.
Xinrun YangJiangsu Provincial Key Lab for Solid Organic Waste Utilization, Key Lab of Organic-based Fertilizers of China, Jiangsu Collaborative Innovation Center for Solid Organic Wastes, Educational Ministry Engineering Center of Resource-saving fertilizers, Nanjing Agricultural University, Nanjing, 210095, China.
Yangchun XuJiangsu Provincial Key Lab for Solid Organic Waste Utilization, Key Lab of Organic-based Fertilizers of China, Jiangsu Collaborative Innovation Center for Solid Organic Wastes, Educational Ministry Engineering Center of Resource-saving fertilizers, Nanjing Agricultural University, Nanjing, 210095, China.
Qirong ShenJiangsu Provincial Key Lab for Solid Organic Waste Utilization, Key Lab of Organic-based Fertilizers of China, Jiangsu Collaborative Innovation Center for Solid Organic Wastes, Educational Ministry Engineering Center of Resource-saving fertilizers, Nanjing Agricultural University, Nanjing, 210095, China.
Tianjie YangJiangsu Provincial Key Lab for Solid Organic Waste Utilization, Key Lab of Organic-based Fertilizers of China, Jiangsu Collaborative Innovation Center for Solid Organic Wastes, Educational Ministry Engineering Center of Resource-saving fertilizers, Nanjing Agricultural University, Nanjing, 210095, China. tjyang@njau.edu.cn.
Zhong WeiJiangsu Provincial Key Lab for Solid Organic Waste Utilization, Key Lab of Organic-based Fertilizers of China, Jiangsu Collaborative Innovation Center for Solid Organic Wastes, Educational Ministry Engineering Center of Resource-saving fertilizers, Nanjing Agricultural University, Nanjing, 210095, China.

Funding

the Key Projects of China National Tobacco Corporation 110202202015the Key Research and Development Project of Guizhou Province of China National Tobacco Corporation 2022XM03the National Natural Science Foundation of China No. 42477125
6 · The paper itself

Abstract

Bacterial wilt caused by Ralstonia solanacearum is one of the most severe plant diseases all over the world. Currently, many scientists are using SynCom (synthetic microbial community) to control this disease. However, designing of highly efficient SynCom remains challenging. In this study, we isolated 372 bacteria with different morphologies from the rhizosphere soil of healthy tobacco plants in a diseased field. Based on the antagonistic activity, compatibility, and presence of cheA gene, a marker gene of chemotaxis, we constructed a chemotactic SynCom comprising two Pseudomonas strains and one Bacillus strain. In vitro experiments revealed that vitamin C, propionic acid, and esculetin significantly promoted the growth and antagonistic ability of chemotactic SynCom strains. Next, we optimized the proportion of organic fertilizer to support the growth of the SynCom strains. The application of the bioorganic fertilizer containing chemotactic SynCom can protect diseased tobacco field from R. solanacearum invasion and enhance yields. Finally, rhizosphere bacterial community analysis showed that phyla Bacillota and Chloroflexiota were significantly enriched. This study highlights the potential of chemotactic SynCom for effective biocontrol, offering a new approach for managing bacterial wilt and enhancing crop yields. KEY POINTS: • The bioorganic fertilizer containing chemotactic SynCom suppresses R. solanacearum and boosts tobacco yields. • Root exudate-selected prebiotics enhance the antagonistic effects of SynCom against pathogens. • SynCom bioorganic fertilizer regulates the rhizosphere microbiome, enriching beneficial bacterial phyla.

Indexed as

ChemotaxisFertilizersNicotianaPlant DiseasesRalstonia solanacearumBacillusBacteriaPseudomonasRhizosphereSoil MicrobiologyFertilizersBacterial wiltBioorganic fertilizerChemotaxisRalstonia solanacearumSynCom

Identifiers

PMID40670700
PMCPMC12267373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.