ReviewNpj imaging2025
Label-free and fluorescence imaging of oligodendrocytes and myelin.
Review in Npj imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Myelin sheaths persist for weeks following axon degeneration.Science advances · 2026Article
- Live-cell physiology in human brain tissue culture-the potential, the challenges, and the lessons learned.Frontiers in cellular neuroscience · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Axonal myelination finely tunes action potential conduction to control precise timing in neural circuits. Little is known about how dynamic myelinating oligodendrocytes are in the adult brain primarily due to limited approaches for their investigation at the cellular level over time in their native environment. This protocol describes optical imaging approaches that allow specific label-free detection of compact myelin which, when combined with genetically encoded fluorescence reporters and small molecule dyes, permits high-resolution longitudinal and fixed sample imaging of myelin and oligodendrocytes in live mice, in live organotypic slices, and in postmortem tissues. Data generated with these approaches can be used to test fundamental questions related to myelin development, plasticity, maintenance, and repair.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.