Evidence map›Paper›PMID 40670624›Full record

ArticleSurgical endoscopy2025

Are outcomes of giant ventral hernia repair inferior? A propensity-matched analysis.

Samantha W Kerr, Brittany S Mead, Alexis M Holland, William R Lorenz, Gregory T Scarola, Kent W Kercher, Vedra A Augenstein, B Todd Heniford, Sullivan A Ayuso

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Samantha W KerrDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.ORCID http://orcid.org/0000-0003-3320-7975
Brittany S MeadDepartment of Minimally Invasive and Bariatric Surgery, Rush University Medical Center, Chicago, IL, USA.
Alexis M HollandDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
William R LorenzDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Gregory T ScarolaDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Kent W KercherDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
Vedra A AugensteinDivision of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, Charlotte, NC, USA.
B Todd HenifordDivision of Gastrointestinal and General Surgery, Department of Surgery, Endeavor Health, Evanston, IL, USA.
Sullivan A AyusoDivision of Gastrointestinal and General Surgery, Department of Surgery, Endeavor Health, Evanston, IL, USA. Sullivan.Ayuso@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVentral hernia repair (VHR) of large defects poses significant technical challenges due to the size of the hernia and complexity of operative techniques required for fascial closure. This study examined clinical outcomes in "giant" open VHR (GVHR), with hernia defect size (HDS) ≥ 200 cm

methodsA prospectively-maintained database from a tertiary hernia center was reviewed for patients undergoing open VHR. 1:1 propensity-score matching was performed for GVHR versus NGVHR based on age, BMI, comorbidities, fascial defect closure, primary vs recurrent repair, CDC wound class, and ASA score. A multivariable regression model evaluated whether wound complications increased odds of recurrence. CDC class III/IV wounds and concomitant intraabdominal procedures were excluded. Standard statistical analyses were performed.

resultsPSM yielded 254 well-matched pairs (all p > 0.05). Average age (59.7 ± 11.3 vs. 59.3 ± 12.3 years) and BMI (32.1 ± 6.5 vs. 32.4 ± 6.6 kg/m

conclusionGVHR often required chemical and mechanical component separation to achieve fascial closure. However, with large preperitoneal mesh overlap and fascial closure, outcomes of large defects in VHR are comparable to smaller defects.

Indexed as

Hernia, VentralHerniorrhaphyAgedFemaleHumansMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRecurrenceRetrospective StudiesTreatment OutcomeAbdominal wall reconstructionComponent separationHerniaWound complications

Identifiers

PMID40670624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.