ArticleScientific reports2025
Retrospective analysis of IMA ligation level effects on nodal dissection and anastomosis in colorectal cancer.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
This study compared the outcomes of high versus low inferior mesenteric artery (IMA) ligation in 380 patients undergoing surgery for rectal or sigmoid colon cancer, with intraoperative indocyanine green (ICG) fluorescence angiography used to assess anastomotic perfusion. The high ligation group demonstrated significantly greater lymph node yield (13 vs.12 p < 0.001) and was associated with more advanced T/N stages, while operative time was longer (218 ± 45 vs. 189 ± 38 min, p < 0.001). ICG navigation enabled objective blood supply evaluation, resulting in no ischemia-related anastomotic leaks and comparable overall complication rates (3.1% vs. 3.4%, p = 0.82). These findings highlight that high ligation improves oncologic resection completeness through extended lymphadenectomy, whereas ICG fluorescence technology enhances anastomotic safety by providing real-time perfusion assessment, offering a dual advantage in colorectal cancer surgery.
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