Evidence map›Paper›PMID 40670401›Full record

ArticleScientific data2025

Time-resolved transcriptomics of S. cerevisiae and S. pastorianus in response to plasma membrane stresses.

Yuta Yamazaki, Fumihiko Omura, Eiichiro Ono, Nozomu Kamada, Keiko Kono

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuta YamazakiOkinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna, Okinawa, 904-0495, Japan.ORCID 0000-0001-5323-6007
Fumihiko OmuraResearch Institute, Suntory Global Innovation Center (SIC) Ltd., 8-1-1 Seikadai, Seika, Soraku, Kyoto, 619-0284, Japan.
Eiichiro OnoResearch Institute, Suntory Global Innovation Center (SIC) Ltd., 8-1-1 Seikadai, Seika, Soraku, Kyoto, 619-0284, Japan.ORCID 0000-0003-0238-6480
Nozomu KamadaResearch Institute, Suntory Global Innovation Center (SIC) Ltd., 8-1-1 Seikadai, Seika, Soraku, Kyoto, 619-0284, Japan.
Keiko KonoOkinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna, Okinawa, 904-0495, Japan. keiko.kono@oist.jp.ORCID 0000-0003-4057-8790

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 23KJ2138MEXT | Japan Society for the Promotion of Science (JSPS) 24K02233MEXT | JST | Center of Innovation Program (COI) JPMJPF2205
6 · The paper itself

Abstract

Yeasts are beneficial microorganisms for human society and are utilized for academic and industrial purposes. For academic purposes, S. cerevisiae is a well-investigated model for studying eukaryotic cellular processes. For industrial purposes, S. pastorianus, which has a hybrid genome of S. cerevisiae and S. eubayanus, has been served for lager beer production. During fermentation, S. pastorianus produces ~7% of EtOH, which induces plasma membrane (PM)/cell wall stress in yeast. Therefore, S. pastorianus may experience PM stress and adapt to the self-forming environment during fermentation. However, how yeast adapts to PM stress remains unclear. Here, we investigated the temporal cellular responses of S. cerevisiae and S. pastorianus during adaptation to PM stresses by time-resolved mRNA-seq analysis. Our data showed different transcriptional phenotypes between S. cerevisiae and S. pastorianus during adaptation. The results may reflect the distinct nature of the two yeasts that have evolved in different nutritional environments. The dataset presented here would provide a promising resource for studying the characteristic nature of these differentially domesticated yeasts upon PM stresses.

Indexed as

Cell MembraneSaccharomycesSaccharomyces cerevisiaeStress, PhysiologicalTranscriptomeAdaptation, PhysiologicalFermentation

Identifiers

PMID40670401
PMCPMC12267428

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.