Evidence map›Paper›PMID 40670341›Full record

ArticleNature communications2025

Mechanically robust neuroprotective stent by sequential Mg ions release for ischemic stroke therapy.

Hongkang Zhang, Yang Zhang, Lili Sheng, Xiaofeng Cao, Chuanjie Wu, Baoying Song, Yunong Shen, Zikai Xu, Ge Song, Hao Sun and 5 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Advanced Therapeutic Approach Based on LDHs-Mimetic Oxidoreductase.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hongkang Zhang *School of Materials Science and Engineering, Peking University, Beijing, China.ORCID http://orcid.org/0009-0009-8441-4916
Yang Zhang *China-America Institute of Neuroscience and and Beijing Institute of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0002-7857-7147
Lili Sheng *Beijing Advanced Medical Technologies, Ltd. Inc, Beijing, China.
Xiaofeng CaoSchool of Materials Science and Engineering, Peking University, Beijing, China.
Chuanjie WuChina-America Institute of Neuroscience and and Beijing Institute of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, China.
Baoying SongDepartment of Neurology and Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yunong ShenSchool of Materials Science and Engineering, Peking University, Beijing, China.
Zikai XuSchool of Life science University of Glasgow, Scotland, UK.
Ge SongBeijing Advanced Medical Technologies, Ltd. Inc, Beijing, China.
Hao SunBeijing Advanced Medical Technologies, Ltd. Inc, Beijing, China.
Qing LiuBeijing Advanced Medical Technologies, Ltd. Inc, Beijing, China.
Xunming JiChina-America Institute of Neuroscience and and Beijing Institute of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, China. jixm@ccmu.edu.cn.ORCID http://orcid.org/0000-0003-0293-2744
Miaowen JiangBeijing Institute of Brain Disorders, Capital Medical University, Beijing, China. jiangmiaowen415@163.com.
Ming LiChina-America Institute of Neuroscience and and Beijing Institute of Geriatrics, Xuanwu Hospital, Capital Medical University, Beijing, China. liming@xwhosp.org.ORCID http://orcid.org/0000-0001-5823-8108
Yufeng ZhengSchool of Materials Science and Engineering, Peking University, Beijing, China. yfzheng@pku.edu.cn.ORCID http://orcid.org/0000-0002-7402-9979

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82027802National Natural Science Foundation of China (National Science Foundation of China) 82102220
6 · The paper itself

Abstract

Most acute ischemic stroke patients with large vessel occlusion require stent implantation post-thrombectomy for complete recanalization, yet they exhibit a high rate of poor prognosis due to ischemia-reperfusion injury. Thus, combining reperfusion therapy with neuroprotective treatment offers significant advantages. This study introduces a novel Mg

Indexed as

Brain IschemiaDrug-Eluting StentsIschemic StrokeMagnesiumNeuroprotective AgentsAnimalsDisease Models, AnimalHumansInfarction, Middle Cerebral ArteryMaleNeuronsPolyestersPrinting, Three-DimensionalRatsRats, Sprague-DawleyReperfusion InjuryMagnesiumNeuroprotective AgentsPolyesters

Identifiers

PMID40670341
PMCPMC12267439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.