Evidence map›Paper›PMID 40670103›Full record

ArticleInternal medicine (Tokyo, Japan)2026

Complete Remission of Acute-onset Autoimmune Hepatitis Following Transcatheter Splenic Arterial Embolization and Splenectomy for Spontaneous Splenic Rupture.

Ikue Sekai, Masahiro Takita, Shigenobu Yasuhara, Naoya Omaru, Takuya Matsubara, Masahiro Morita, Hirokazu Chishina, Kosuke Minaga, Satoru Hagiwara, Hiroshi Ida and 4 more

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ikue SekaiDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Masahiro TakitaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Shigenobu YasuharaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Naoya OmaruDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Takuya MatsubaraDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Masahiro MoritaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Hirokazu ChishinaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Kosuke MinagaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Satoru HagiwaraDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Hiroshi IdaDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Misa KojimaDepartment of Pathology, Kindai University Faculty of Medicine, Japan.
Osamu MaenishiDepartment of Pathology, Kindai University Faculty of Medicine, Japan.
Tomohiro WatanabeDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.
Masatoshi KudoDepartment of Gastroenterology and Hepatology, Kindai University Faculty of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 62-year-old woman presented with jaundice and fatigue. A blood examination revealed markedly elevated serum transaminase and bilirubin levels and negative hepatitis virus markers. A radiographic examination revealed no bile duct abnormalities. Serum transaminase levels decreased and normalized without immunosuppression after transcatheter arterial embolization and splenectomy for spontaneous splenic rupture, respectively. The pathological findings of the liver biopsy specimens were consistent with those of acute-onset autoimmune hepatitis (AIH), despite normal serum IgG levels. The clinical course of the present case suggests that pathogenic immune responses associated with acute-onset AIH may arise in the spleen, but not in the liver.

Indexed as

Embolization, TherapeuticHepatitis, AutoimmuneSplenectomySplenic RuptureAcute DiseaseFemaleHumansMiddle AgedRemission InductionRupture, SpontaneousSplenic Arteryautoimmune hepatitisspleensplenectomyspontaneous splenic rupture

Identifiers

PMID40670103
PMCPMC12945422

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.