Evidence map›Paper›PMID 40670064›Full record

ArticleNeurosciences (Riyadh, Saudi Arabia)2025

Platelet reactivity to adenosine diphosphate and

Hongting Shi, Mingzhu Tang, Tiezhu Wang, Lihua Yang, Xuanming Lai, Yongyuan Chen, Fangming Diao, Xiaolian Chen, Jinxi Zuo, Junyang Xu and 2 more

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Article in Neurosciences (Riyadh, Saudi Arabia), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hongting ShiFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Mingzhu TangFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Tiezhu WangFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Lihua YangFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Xuanming LaiFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Yongyuan ChenFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Fangming DiaoFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Xiaolian ChenFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Jinxi ZuoFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Junyang XuFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Gaoxian ZhongFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.
Yaxian DongFrom the Department of Neurology (Shi, Tang, Wang, Yang, Lai, Diao, Chen, Zuo, Xu, Zhong, Dong), Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, and the Department of Neurology (Chen), The Fifth Affiliated Hospital of Guangzhou Medical University.ORCID https://orcid.org/0009-0000-1841-3303

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the correlations of ADP-induced platelet-inhibition rate (ADP-PIR) and

methodsWe retrospectively evaluated the data of AIS patients treated at our hospital during 2019-2022, and administered maintenance clopidogrel (75 mg/d). Carotid plaques, ADP-PIR, and

resultsOf 692 study patients, 378 (54.6%) and 128 (18.5%) had unstable and stable carotid plaques, respectively. Multivariate logistic regression identified PIR and

conclusionThe PIR and

Indexed as

Adenosine DiphosphateBlood PlateletsCarotid StenosisCytochrome P-450 CYP2C19Ischemic StrokePlaque, AtheroscleroticAgedClopidogrelFemaleGenotypeHumansMaleMiddle AgedPlatelet Aggregation InhibitorsRetrospective StudiesAdenosine DiphosphateClopidogrelCYP2C19 protein, humanCytochrome P-450 CYP2C19Platelet Aggregation Inhibitors

Identifiers

PMID40670064
PMCPMC12279339

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.