Evidence map›Paper›PMID 40670061›Full record

SynthesisNeurosciences (Riyadh, Saudi Arabia)2025

Association of sarcopenic obesity with cognitive dysfunction: A systematic review and meta-analysis.

Qi Wu, Siye Xie, Jinhong Ying

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Neurosciences (Riyadh, Saudi Arabia), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qi WuFrom the Department of Nursing (Wu), Department of Operating Room (Ying), The First Affiliated Hospital, Zhejiang University School of Medicine, and from the School of Nursing (Xie), Zhejiang Chinese Medical University, Hangzhou, China.ORCID https://orcid.org/0000-0003-0499-0577
Siye XieFrom the Department of Nursing (Wu), Department of Operating Room (Ying), The First Affiliated Hospital, Zhejiang University School of Medicine, and from the School of Nursing (Xie), Zhejiang Chinese Medical University, Hangzhou, China.
Jinhong YingFrom the Department of Nursing (Wu), Department of Operating Room (Ying), The First Affiliated Hospital, Zhejiang University School of Medicine, and from the School of Nursing (Xie), Zhejiang Chinese Medical University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the association between sarcopenic obesity and cognitive dysfunction. Changes in human body composition may be linked to the development of cognitive dysfunction. Sarcopenic obesity, characterized by excessive fat accumulation and reduced muscle mass, is implicated in various adverse health outcomes.

methodsWe conducted a systematic review and meta-analysis. PubMed, Cochrane Library, Web of Science, Embase, CINAHL, CNKI, Sinomed, Wanfang, and VIP databases were searched for studies examining the link between sarcopenic obesity and cognitive dysfunction. The process adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.

resultsEight studies, comprising 87,520 participants (5 cohort and 3 cross-sectional studies) were included. Meta-analysis using a random effects model addressed high heterogeneity (

conclusionSarcopenic obesity is associated with cognitive dysfunction. However, further research utilizing standardized diagnostic criteria and methodologies is essential to corroborate these findings.

Indexed as

Cognitive DysfunctionObesitySarcopeniaHumans

Identifiers

PMID40670061
PMCPMC12279332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.