Evidence map›Paper›PMID 40669907›Full record

ArticleBMJ open2025

Time to full recovery and its predictors among children with complicated severe acute malnutrition admitted to inpatient and subsequently to outpatient therapeutic care, Sana'a city, Yemen, a prospective follow-up study.

Mohammed Abdullah Al Amad, Yahia Ahmed Raja'a, Khaled Algendari

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Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Mohammed Abdullah Al AmadCommunity Medicine, Sana'a University Faculty of Medicine and Health Sciences, Sana'a, Capital Municipality, Yemen mohammed.al-amad@su.edu.ye.ORCID http://orcid.org/0000-0002-1566-4964
Yahia Ahmed Raja'aCommunity Medicine, Sana'a University Faculty of Medicine and Health Sciences, Sana'a, Capital Municipality, Yemen.
Khaled AlgendariCommunity Medicine, Sana'a University Faculty of Medicine and Health Sciences, Sana'a, Capital Municipality, Yemen.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the time to full recovery and its predictors among children with severe acute malnutrition (SAM) admitted to therapeutic feeding centres (TFCs) in Sana'a, Yemen.

designA prospective cohort study conducted from August 2023 to November 2024.

settingTwo public hospitals in Sana'a City (Al-Sabeen and Al-Zubairi hospital) that provide therapeutic feeding services for children with SAM.

participantsChildren aged 6-59 months who were admitted to TFCs based on WHO SAM criteria and successfully transferred to outpatient therapeutic programmes (OTPs). OUTCOME MEASURES: The primary outcome was time to full recovery from SAM, defined as the normalisation of both weight-for-height z-score (WHZ) and mid-upper arm circumference (MUAC). Secondary outcomes included identification of predictors associated with recovery time.

resultsAmong 267 children, 51% were aged 6 to <12 months and 56% were female. The median time to full recovery was 14 weeks (IQR: 12-18 weeks). Children admitted with concurrent deficiency in both WHZ <-3 and MUAC<11.5 cm had a 50% lower likelihood of full recovery (adjusted HR (aHR): 0.5; 95% CI: 0.3 to 0.9; p=0.015). Antibiotic use during OTP care nearly doubled the likelihood of recovery (aHR: 2.1; 95% CI: 1.2 to 3.4; p=0.002), while the presence of diarrhoea lowered the likelihood of full recovery by 50% (aHR: 0.5; 95% CI: 0.3 to 0.9; p=0.011).

conclusionThree months and a half were the median time to full recovery from complicated SAM. Concurrent WHZ and MUAC deficits, antibiotic use and the absence of diarrhoea were the significant predictors. Standardising the use of combined WHZ and MUAC recovery is recommended to improve comparability across programmes and better reflect nutritional outcomes.

Indexed as

Ambulatory CareSevere Acute MalnutritionChild, PreschoolFemaleFollow-Up StudiesHospitalizationHumansInfantMaleProspective StudiesTime FactorsYemenCommunity child healthObservational StudyRehabilitation Medicine

Identifiers

PMID40669907
PMCPMC12273129

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