Evidence map›Paper›PMID 40669895›Full record

ArticleBMJ open2025

Optimising Paediatric Transition to Intensive Care for Adults (OPTICAL): study protocol for a mixed method study.

Qi Huang, Charmaine Kohn, Sue Ben Abraham, Katherine Malbon, Anjalika Mallick, Paul R Mouncey, Kate Oulton, Christina Pagel, Louise Rose, Sarah E Seaton and 6 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Qi HuangUniversity College London Clinical Operational Research Unit, London, UK qi_huang@ucl.ac.uk.ORCID http://orcid.org/0000-0003-4456-2999
Charmaine KohnCentre for Outcomes and Experience Research in Children's Health, Illness and Disability, Great Ormond Street Hospital for Children, London, UK.
Sue Ben AbrahamPatient and Public Involvement and Engagement (PPIE) Advisor and Representative, London, UK.
Katherine MalbonPaediatric Critical Care, Imperial College London Department of Surgery and Cancer, London, UK.
Anjalika MallickPaediatric Critical Care, Imperial College London Department of Surgery and Cancer, London, UK.
Paul R MounceyClinical Trials Unit, Intensive Care National Audit and Research Centre, London, UK.ORCID http://orcid.org/0000-0002-8510-8517
Kate OultonCentre for Outcomes and Experience Research in Children's Health, Illness and Disability, Great Ormond Street Hospital for Children, London, UK.
Christina PagelUniversity College London Clinical Operational Research Unit, London, UK.ORCID http://orcid.org/0000-0002-2857-1628
Louise RoseKing's College London Florence Nightingale Faculty of Nursing Midwifery and Palliative Care, London, UK.ORCID http://orcid.org/0000-0003-1700-3972
Sarah E SeatonUniversity of Leicester Department of Population Health Sciences, Leicester, UK.ORCID http://orcid.org/0000-0001-8711-4817
Julie TaylorUniversity College London Clinical Operational Research Unit, London, UK.ORCID http://orcid.org/0000-0002-7698-6991
Rum ThomasPaediatric Critical Care, Sheffield Children's Hospital NHS Foundation Trust, Sheffield, UK.
Clare WindsorRotherham NHS Foundation Trust, Rotherham, UK.
Jo WrayCentre for Outcomes and Experience Research in Children's Health, Illness and Disability, Great Ormond Street Hospital for Children, London, UK.ORCID http://orcid.org/0000-0002-4769-1211
Padmanabhan RamnarayanPaediatric Critical Care, Imperial College London Department of Surgery and Cancer, London, UK.
Sonya CroweUniversity College London Clinical Operational Research Unit, London, UK.ORCID http://orcid.org/0000-0003-1882-5476

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAn increasing number of teenagers and young adults (TYA) with chronic conditions and complex needs are transitioning from paediatric to adult services, including admission to intensive care units (ICUs). As these services are often ill-equipped to care for TYA, there is a risk of compromised care. Despite recent guidelines from the UK Paediatric Critical Care and Intensive Care Societies highlighting the importance and urgency of improving ICU transition, current recommendations are not evidence-based and established pathways for ICU transition remain limited. METHODS AND ANALYSIS: This mixed-methods research study aims to generate evidence to underpin national policy on transition from paediatric to adult ICUs that will improve clinical care and patient experience. To do this, we will: (1) link and analyse UK national data (years 2017-2024) on paediatric and adult ICU admissions, hospital inpatient, outpatient and emergency care visits and survival status, to determine the clinical characteristics and healthcare resource utilisation from teenage years to early adulthood of people admitted to an ICU as a young person (admission aged 14 and 15), and how these relate to ICU admissions after age 16; (2) conduct semistructured interviews, online forums and surveys with TYA patients, carers and health professionals to understand their experience of transition in ICU services; and (3) synthesise these strands of evidence and use a structured process of stakeholder engagement to propose potential targeted improvements as appropriate. ETHICS AND DISSEMINATION: This study was approved by the East of England - Cambridge South Research Ethics Committee on 1 August 2024 (research ethics committee number 24/EE/0108), and the Health Research Authority Confidentiality Advisory Group (CAG) on 7 October 2024 (CAG number 24/CAG/0068). Study results will be actively disseminated through peer-reviewed journals, conference presentations and accessible lay texts and graphic summaries for the use of charities and patients including those with learning disabilities and neurodevelopmental disorders.

Indexed as

Critical CareIntensive Care UnitsTransition to Adult CareAdolescentHumansResearch DesignUnited KingdomYoung AdultAdolescentAdult intensive & critical carePaediatric intensive & critical care

Identifiers

PMID40669895
PMCPMC12273106

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.