Evidence map›Paper›PMID 40669892›Full record

ArticleBMJ open2025

Imaging analysis using Artificial Intelligence to predict outcomes after endovascular aortic aneurysm repair: protocol for a retrospective cohort study.

Fabien Lareyre, Juliette Raffort, Stavros K Kakkos, Mario D'Oria, Bahaa Nasr, Athanasios Saratzis, George A Antoniou, Robert J Hinchliffe, European Research Hub Working Group

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fabien LareyreDepartment of Vascular Surgery, Hospital of Antibes, Antibes, France fabien.lareyre@gmail.com.ORCID http://orcid.org/0000-0002-6765-8021
Juliette RaffortFédération Hospitalo-Universitaire FHU Plan, Nice, France.
Stavros K KakkosDepartment of Vascular Surgery, University Hospital of Patras, Patras, Greece.
Mario D'OriaDivision of Vascular and Endovascular Surgery, Cardio-Thoraco-Vascular Department, University Hospital of Trieste ASUGI, Trieste, Italy.ORCID http://orcid.org/0000-0002-7156-7827
Bahaa NasrDepartment of Vascular and Endovascular Surgery, Univ Brest, CHU Brest, UMR 1101 LaTIM, Brest, France.
Athanasios SaratzisDepartment of Cardiovascular Sciences, National Institute for Health and Care Research Leicester Biomedical Research Center (NIHR BRC), Glenfield Hospital, University of Leicester, Leicester, UK.
George A AntoniouManchester Vascular Centre, Manchester University NHS Foundation Trust, Manchester, UK and Division of Cardiovascular Sciences, School of Medical Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
Robert J HinchliffeNorth Bristol NHS Trust and University of Bristol, Bristol, UK.
European Research Hub Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEndovascular aortic aneurysm repair (EVAR) requires long-term surveillance to detect and treat postoperative complications. However, prediction models to optimise follow-up strategies are still lacking. The primary objective of this study is to develop predictive models of post-operative outcomes following elective EVAR using Artificial Intelligence (AI)-driven analysis. The secondary objective is to investigate morphological aortic changes following EVAR. METHODS AND ANALYSIS: This international, multicentre, observational study will retrospectively include 500 patients who underwent elective EVAR. Primary outcomes are EVAR postoperative complications including deaths, re-interventions, endoleaks, limb occlusion and stent-graft migration occurring within 1 year and at mid-term follow-up (1 to 3 years). Secondary outcomes are aortic anatomical changes. Morphological changes following EVAR will be analysed and compared based on preoperative and postoperative CT angiography (CTA) images (within 1 to 12 months, and at the last follow-up) using the AI-based software PRAEVAorta 2 (Nurea). Deep learning algorithms will be applied to stratify the risk of postoperative outcomes into low or high-risk categories. The training and testing dataset will be respectively composed of 70% and 30% of the cohort. ETHICS AND DISSEMINATION: The study protocol is designed to ensure that the sponsor and the investigators comply with the principles of the Declaration of Helsinki and the ICH E6 good clinical practice guideline. The study has been approved by the ethics committee of the University Hospital of Patras (Patras, Greece) under the number 492/05.12.2024. The results of the study will be presented at relevant national and international conferences and submitted for publication to peer-review journals.

Indexed as

Aortic AneurysmAortic Aneurysm, AbdominalArtificial IntelligenceEndovascular ProceduresPostoperative ComplicationsComputed Tomography AngiographyHumansMulticenter Studies as TopicObservational Studies as TopicRetrospective StudiesTreatment OutcomeArtificial IntelligenceCardiovascular imagingMachine LearningVascular surgery

Identifiers

PMID40669892
PMCPMC12273115

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.