ArticleNeurology2025
Racial and Ethnic Differences in Peripheral Neuropathy Risk Factors Among United States Adults.
Article in Neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Epidemiology, Presentation, Management and Outcomes in Chronic Inflammatory Demyelinating Polyneuropathy in Birmingham, UK: The Impact of Ethnicity.Journal of the peripheral nervous system : JPNS · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
BACKGROUND AND
objectivesPeripheral neuropathy (PN) is a morbid condition. In the United States, there is higher prevalence of PN in non-Hispanic Black and Hispanic individuals vs non-Hispanic White individuals. Underlying mechanisms driving this increased prevalence are unknown. We aimed to determine associations between PN and race/ethnicity; other demographic information; and metabolic, lifestyle, and social determinants of health (SDOH) risk factors in a large and diverse sample of adults from the United States.
methodsWe performed a cross-sectional secondary analysis of the National Health and Nutrition Examination Survey from 1999 to 2004. PN was assessed using a monofilament test of reduced sensation. Risk factors included demographic (age, sex, race/ethnicity), metabolic (height, weight, waist circumference, systolic blood pressure, high-density lipoproteins, HbA1c), lifestyle (physical activity, diet), and SDOH (food security, household income, health insurance) information.
resultsThe study included 8,014 individuals (55% non-Hispanic White, 18% non-Hispanic Black, 24% Hispanic, 3% other). The mean (SD) age was 60.8 (13.3) years, and 50% were female. Logistic regression revealed that non-Hispanic Black (odds ratio: 1.39, 95% CI 1.16-1.66) and Hispanic (1.31, 1.11-1.54) individuals had higher age-adjusted and sex-adjusted odds of PN than White individuals. Male individuals had higher age-adjusted and race-adjusted odds of PN than female individuals (0.55, 0.48-0.63). After adjusting for metabolic, lifestyle, and SDOH factors, we found that non-Hispanic Black individuals had similar odds of PN to White individuals (1.17, 0.93-1.46, DISCUSSION: We found that PN risk factors likely explain higher PN prevalence in non-Hispanic Black individuals but not among Hispanic individuals. We also determined SDOH risk factors-including being uninsured, and, in Hispanic individuals, experiencing food insecurity-increased the odds of PN, indicating the need for screening, prevention, and treatment of PN in persons with SDOH risk factors.
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